node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc28b | Tmem234 | ENSMUSP00000030586 | ENSMUSP00000099651 | Coiled-coil domain-containing protein 28B; Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex. | Transmembrane protein 234. | 0.555 |
Cmbl | Tcp11l2 | ENSMUSP00000070314 | ENSMUSP00000020223 | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | 0.433 |
Cmbl | Tmem234 | ENSMUSP00000070314 | ENSMUSP00000099651 | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | Transmembrane protein 234. | 0.499 |
Cmbl | Xkrx | ENSMUSP00000070314 | ENSMUSP00000033611 | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | XK-related protein 2. | 0.427 |
Mmadhc | Tcp11l2 | ENSMUSP00000099830 | ENSMUSP00000020223 | Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC. | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | 0.462 |
Mmadhc | Tmem234 | ENSMUSP00000099830 | ENSMUSP00000099651 | Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC. | Transmembrane protein 234. | 0.549 |
Mmadhc | Xkrx | ENSMUSP00000099830 | ENSMUSP00000033611 | Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC. | XK-related protein 2. | 0.459 |
Mrps17 | Sra1 | ENSMUSP00000112779 | ENSMUSP00000133360 | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. | Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N- terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis (By similarity). Belongs to the SRA1 family. | 0.589 |
Mrps17 | Tmem234 | ENSMUSP00000112779 | ENSMUSP00000099651 | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. | Transmembrane protein 234. | 0.449 |
Sra1 | Mrps17 | ENSMUSP00000133360 | ENSMUSP00000112779 | Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N- terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis (By similarity). Belongs to the SRA1 family. | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. | 0.589 |
Sra1 | Tmem234 | ENSMUSP00000133360 | ENSMUSP00000099651 | Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N- terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis (By similarity). Belongs to the SRA1 family. | Transmembrane protein 234. | 0.561 |
Tcp11l2 | Cmbl | ENSMUSP00000020223 | ENSMUSP00000070314 | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | 0.433 |
Tcp11l2 | Mmadhc | ENSMUSP00000020223 | ENSMUSP00000099830 | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC. | 0.462 |
Tcp11l2 | Tmem234 | ENSMUSP00000020223 | ENSMUSP00000099651 | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | Transmembrane protein 234. | 0.619 |
Tcp11l2 | Xkrx | ENSMUSP00000020223 | ENSMUSP00000033611 | T-complex protein 11-like protein 2; Belongs to the TCP11 family. | XK-related protein 2. | 0.634 |
Tmem234 | Ccdc28b | ENSMUSP00000099651 | ENSMUSP00000030586 | Transmembrane protein 234. | Coiled-coil domain-containing protein 28B; Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex. | 0.555 |
Tmem234 | Cmbl | ENSMUSP00000099651 | ENSMUSP00000070314 | Transmembrane protein 234. | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | 0.499 |
Tmem234 | Mmadhc | ENSMUSP00000099651 | ENSMUSP00000099830 | Transmembrane protein 234. | Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC. | 0.549 |
Tmem234 | Mrps17 | ENSMUSP00000099651 | ENSMUSP00000112779 | Transmembrane protein 234. | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. | 0.449 |
Tmem234 | Sra1 | ENSMUSP00000099651 | ENSMUSP00000133360 | Transmembrane protein 234. | Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N- terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis (By similarity). Belongs to the SRA1 family. | 0.561 |