node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AU040320 | Cpd | ENSMUSP00000099667 | ENSMUSP00000021201 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Carboxypeptidase D; Belongs to the peptidase M14 family. | 0.578 |
AU040320 | Dcdc2a | ENSMUSP00000099667 | ENSMUSP00000063650 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | 0.689 |
AU040320 | Dip2a | ENSMUSP00000099667 | ENSMUSP00000043710 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Disco-interacting protein 2 homolog A; May provide positional cues for axon pathfinding and patterning in the central nervous system; Belongs to the DIP2 family. | 0.501 |
AU040320 | Dnaaf4 | ENSMUSP00000099667 | ENSMUSP00000034734 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | 0.618 |
AU040320 | Fam91a1 | ENSMUSP00000099667 | ENSMUSP00000036524 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1. | 0.553 |
AU040320 | Gpr108 | ENSMUSP00000099667 | ENSMUSP00000156910 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Protein GPR108; Belongs to the LU7TM family. | 0.486 |
AU040320 | Jun | ENSMUSP00000099667 | ENSMUSP00000102711 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 (By similarity). Binds to the USP28 promoter (By similarity). | 0.426 |
AU040320 | Rubcn | ENSMUSP00000099667 | ENSMUSP00000087114 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein; Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (By similarity). | 0.467 |
AU040320 | Tlk2 | ENSMUSP00000099667 | ENSMUSP00000102554 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly (By similarity). Negative regulator of amino acid starvation-induced autophagy (By similarity). | 0.425 |
AU040320 | Vps54 | ENSMUSP00000099667 | ENSMUSP00000006221 | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling. | 0.434 |
Cpd | AU040320 | ENSMUSP00000021201 | ENSMUSP00000099667 | Carboxypeptidase D; Belongs to the peptidase M14 family. | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | 0.578 |
Cpd | Fam91a1 | ENSMUSP00000021201 | ENSMUSP00000036524 | Carboxypeptidase D; Belongs to the peptidase M14 family. | Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1. | 0.612 |
Dcdc2a | AU040320 | ENSMUSP00000063650 | ENSMUSP00000099667 | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | 0.689 |
Dcdc2a | Dip2a | ENSMUSP00000063650 | ENSMUSP00000043710 | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | Disco-interacting protein 2 homolog A; May provide positional cues for axon pathfinding and patterning in the central nervous system; Belongs to the DIP2 family. | 0.404 |
Dcdc2a | Dnaaf4 | ENSMUSP00000063650 | ENSMUSP00000034734 | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | 0.897 |
Dip2a | AU040320 | ENSMUSP00000043710 | ENSMUSP00000099667 | Disco-interacting protein 2 homolog A; May provide positional cues for axon pathfinding and patterning in the central nervous system; Belongs to the DIP2 family. | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | 0.501 |
Dip2a | Dcdc2a | ENSMUSP00000043710 | ENSMUSP00000063650 | Disco-interacting protein 2 homolog A; May provide positional cues for axon pathfinding and patterning in the central nervous system; Belongs to the DIP2 family. | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | 0.404 |
Dnaaf4 | AU040320 | ENSMUSP00000034734 | ENSMUSP00000099667 | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | 0.618 |
Dnaaf4 | Dcdc2a | ENSMUSP00000034734 | ENSMUSP00000063650 | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity). | 0.897 |
Fam91a1 | AU040320 | ENSMUSP00000036524 | ENSMUSP00000099667 | Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1. | Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R. | 0.553 |