node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdk5rap1 | Gtpbp6 | ENSMUSP00000105353 | ENSMUSP00000076458 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | Putative GTP-binding protein 6. | 0.407 |
Cdk5rap1 | Mtfmt | ENSMUSP00000105353 | ENSMUSP00000074347 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity); Belongs to the Fmt family. | 0.455 |
Cdk5rap1 | Osgepl1 | ENSMUSP00000105353 | ENSMUSP00000110128 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Belongs to the KAE1 / TsaD family. | 0.674 |
Cdk5rap1 | Trit1 | ENSMUSP00000105353 | ENSMUSP00000099709 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | 0.873 |
Cdk5rap1 | Trmt5 | ENSMUSP00000105353 | ENSMUSP00000112121 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | tRNA (guanine(37)-N1)-methyltransferase; Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. | 0.645 |
Cdk5rap1 | Trmu | ENSMUSP00000105353 | ENSMUSP00000023019 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. | 0.731 |
Cdk5rap1 | Yrdc | ENSMUSP00000105353 | ENSMUSP00000099688 | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | YrdC domain-containing protein, mitochondrial; May regulate the activity of some transporters. | 0.625 |
Ftsj1 | Trit1 | ENSMUSP00000033513 | ENSMUSP00000099709 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | 0.858 |
Ftsj1 | Trmt5 | ENSMUSP00000033513 | ENSMUSP00000112121 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA (guanine(37)-N1)-methyltransferase; Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. | 0.565 |
Gtpbp6 | Cdk5rap1 | ENSMUSP00000076458 | ENSMUSP00000105353 | Putative GTP-binding protein 6. | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | 0.407 |
Gtpbp6 | Mrm2 | ENSMUSP00000076458 | ENSMUSP00000031536 | Putative GTP-binding protein 6. | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.705 |
Gtpbp6 | Trit1 | ENSMUSP00000076458 | ENSMUSP00000099709 | Putative GTP-binding protein 6. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | 0.838 |
Lta4h | Trit1 | ENSMUSP00000016033 | ENSMUSP00000099709 | Leukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | 0.885 |
Mrm2 | Gtpbp6 | ENSMUSP00000031536 | ENSMUSP00000076458 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | Putative GTP-binding protein 6. | 0.705 |
Mrm2 | Osgepl1 | ENSMUSP00000031536 | ENSMUSP00000110128 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Belongs to the KAE1 / TsaD family. | 0.409 |
Mrm2 | Trit1 | ENSMUSP00000031536 | ENSMUSP00000099709 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | 0.811 |
Mrm2 | Trmt5 | ENSMUSP00000031536 | ENSMUSP00000112121 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | tRNA (guanine(37)-N1)-methyltransferase; Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. | 0.541 |
Mrm2 | Trmu | ENSMUSP00000031536 | ENSMUSP00000023019 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. | 0.436 |
Mtfmt | Cdk5rap1 | ENSMUSP00000074347 | ENSMUSP00000105353 | Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity); Belongs to the Fmt family. | CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). | 0.455 |
Mtfmt | Osgepl1 | ENSMUSP00000074347 | ENSMUSP00000110128 | Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity); Belongs to the Fmt family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Belongs to the KAE1 / TsaD family. | 0.513 |