node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
5730522E02Rik | Asb3 | ENSMUSP00000105137 | ENSMUSP00000020551 | RIKEN cDNA 5730522E02 gene. | Ankyrin repeat and SOCS box protein 3; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B (By similarity). | 0.489 |
5730522E02Rik | Rasl10b | ENSMUSP00000105137 | ENSMUSP00000132696 | RIKEN cDNA 5730522E02 gene. | Ras-like protein family member 10B; May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure; Belongs to the small GTPase superfamily. Ras family. | 0.529 |
5730522E02Rik | Zfp39 | ENSMUSP00000105137 | ENSMUSP00000099764 | RIKEN cDNA 5730522E02 gene. | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.649 |
Arhgap45 | Zfp39 | ENSMUSP00000101012 | ENSMUSP00000099764 | Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR- domin which is able to play an autoinhibitory effect on this RhoGAP activity. | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.448 |
Asb3 | 5730522E02Rik | ENSMUSP00000020551 | ENSMUSP00000105137 | Ankyrin repeat and SOCS box protein 3; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B (By similarity). | RIKEN cDNA 5730522E02 gene. | 0.489 |
Asb3 | Zfp39 | ENSMUSP00000020551 | ENSMUSP00000099764 | Ankyrin repeat and SOCS box protein 3; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B (By similarity). | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.418 |
Fbxw10 | Zfp39 | ENSMUSP00000135870 | ENSMUSP00000099764 | F-box/WD repeat-containing protein 10; Probable substrate-recognition component of a SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity). | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.671 |
Fgd6 | Zfp39 | ENSMUSP00000020208 | ENSMUSP00000099764 | FYVE, RhoGEF and PH domain-containing protein 6; May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.483 |
Lyrm7 | Zfp39 | ENSMUSP00000120778 | ENSMUSP00000099764 | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity). | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.501 |
Rasl10b | 5730522E02Rik | ENSMUSP00000132696 | ENSMUSP00000105137 | Ras-like protein family member 10B; May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure; Belongs to the small GTPase superfamily. Ras family. | RIKEN cDNA 5730522E02 gene. | 0.529 |
Rasl10b | Zfp39 | ENSMUSP00000132696 | ENSMUSP00000099764 | Ras-like protein family member 10B; May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure; Belongs to the small GTPase superfamily. Ras family. | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.408 |
Rhobtb1 | Zfp39 | ENSMUSP00000065095 | ENSMUSP00000099764 | Rho-related BTB domain-containing protein 1. | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | 0.408 |
Zfp39 | 5730522E02Rik | ENSMUSP00000099764 | ENSMUSP00000105137 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | RIKEN cDNA 5730522E02 gene. | 0.649 |
Zfp39 | Arhgap45 | ENSMUSP00000099764 | ENSMUSP00000101012 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR- domin which is able to play an autoinhibitory effect on this RhoGAP activity. | 0.448 |
Zfp39 | Asb3 | ENSMUSP00000099764 | ENSMUSP00000020551 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | Ankyrin repeat and SOCS box protein 3; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B (By similarity). | 0.418 |
Zfp39 | Fbxw10 | ENSMUSP00000099764 | ENSMUSP00000135870 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | F-box/WD repeat-containing protein 10; Probable substrate-recognition component of a SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity). | 0.671 |
Zfp39 | Fgd6 | ENSMUSP00000099764 | ENSMUSP00000020208 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | FYVE, RhoGEF and PH domain-containing protein 6; May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). | 0.483 |
Zfp39 | Lyrm7 | ENSMUSP00000099764 | ENSMUSP00000120778 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity). | 0.501 |
Zfp39 | Rasl10b | ENSMUSP00000099764 | ENSMUSP00000132696 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | Ras-like protein family member 10B; May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure; Belongs to the small GTPase superfamily. Ras family. | 0.408 |
Zfp39 | Rhobtb1 | ENSMUSP00000099764 | ENSMUSP00000065095 | Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis. | Rho-related BTB domain-containing protein 1. | 0.408 |