node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cetn4 | Eny2 | ENSMUSP00000100020 | ENSMUSP00000052905 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | 0.667 |
Cetn4 | Fam161a | ENSMUSP00000100020 | ENSMUSP00000158891 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Protein FAM161A; Involved in ciliogenesis. | 0.598 |
Cetn4 | Mcm3ap | ENSMUSP00000100020 | ENSMUSP00000125960 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Germinal-center associated nuclear protein; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations ; Belongs to the SAC3 family. | 0.591 |
Cetn4 | Morn1 | ENSMUSP00000100020 | ENSMUSP00000030915 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | MORN repeat-containing 1. | 0.604 |
Cetn4 | Nme8 | ENSMUSP00000100020 | ENSMUSP00000089358 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity). | 0.591 |
Cetn4 | Sac3d1 | ENSMUSP00000100020 | ENSMUSP00000109161 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | SAC3 domain-containing protein 1; Involved in centrosome duplication and mitotic progression. Belongs to the SAC3 family. | 0.591 |
Cetn4 | Sfi1 | ENSMUSP00000100020 | ENSMUSP00000080066 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Protein SFI1 homolog; Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2. | 0.724 |
Cetn4 | Spef1 | ENSMUSP00000100020 | ENSMUSP00000105847 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | Sperm flagellar protein 1; Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock. Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). | 0.668 |
Cetn4 | Tbccd1 | ENSMUSP00000100020 | ENSMUSP00000004576 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.758 |
Cetn4 | Xpc | ENSMUSP00000100020 | ENSMUSP00000032182 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | DNA repair protein complementing XP-C cells homolog; Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen- bonded bases by forming a transient nucleoprotein intermediate complex which ma [...] | 0.641 |
Eny2 | Cetn4 | ENSMUSP00000052905 | ENSMUSP00000100020 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.667 |
Eny2 | Mcm3ap | ENSMUSP00000052905 | ENSMUSP00000125960 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | Germinal-center associated nuclear protein; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations ; Belongs to the SAC3 family. | 0.999 |
Eny2 | Sac3d1 | ENSMUSP00000052905 | ENSMUSP00000109161 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | SAC3 domain-containing protein 1; Involved in centrosome duplication and mitotic progression. Belongs to the SAC3 family. | 0.888 |
Fam161a | Cetn4 | ENSMUSP00000158891 | ENSMUSP00000100020 | Protein FAM161A; Involved in ciliogenesis. | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.598 |
Mcm3ap | Cetn4 | ENSMUSP00000125960 | ENSMUSP00000100020 | Germinal-center associated nuclear protein; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations ; Belongs to the SAC3 family. | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.591 |
Mcm3ap | Eny2 | ENSMUSP00000125960 | ENSMUSP00000052905 | Germinal-center associated nuclear protein; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations ; Belongs to the SAC3 family. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] | 0.999 |
Morn1 | Cetn4 | ENSMUSP00000030915 | ENSMUSP00000100020 | MORN repeat-containing 1. | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.604 |
Morn1 | Tbccd1 | ENSMUSP00000030915 | ENSMUSP00000004576 | MORN repeat-containing 1. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.701 |
Nme8 | Cetn4 | ENSMUSP00000089358 | ENSMUSP00000100020 | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity). | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.591 |
Sac3d1 | Cetn4 | ENSMUSP00000109161 | ENSMUSP00000100020 | SAC3 domain-containing protein 1; Involved in centrosome duplication and mitotic progression. Belongs to the SAC3 family. | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.591 |