node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Boll | Psapl1 | ENSMUSP00000084868 | ENSMUSP00000100594 | Protein boule-like; Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity); Belongs to the RRM DAZ family. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.473 |
Calm4 | Cysrt1 | ENSMUSP00000041636 | ENSMUSP00000140416 | Calmodulin-4; Implicated in the early stage of ectopic ossification. | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | 0.515 |
Calm4 | Krt14 | ENSMUSP00000041636 | ENSMUSP00000007272 | Calmodulin-4; Implicated in the early stage of ectopic ossification. | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. | 0.482 |
Calm4 | Lce1b | ENSMUSP00000041636 | ENSMUSP00000029531 | Calmodulin-4; Implicated in the early stage of ectopic ossification. | Late cornified envelope 1B. | 0.571 |
Calm4 | Lypd3 | ENSMUSP00000041636 | ENSMUSP00000079543 | Calmodulin-4; Implicated in the early stage of ectopic ossification. | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity). | 0.514 |
Calm4 | Psapl1 | ENSMUSP00000041636 | ENSMUSP00000100594 | Calmodulin-4; Implicated in the early stage of ectopic ossification. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.469 |
Cdnf | Psap | ENSMUSP00000046297 | ENSMUSP00000137476 | Cerebral dopamine neurotrophic factor; Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity); Belongs to the ARMET family. | Saposin-B-Val; [Prosaposin]: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta- galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha- galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposins are specific low-mol [...] | 0.648 |
Cdnf | Psapl1 | ENSMUSP00000046297 | ENSMUSP00000100594 | Cerebral dopamine neurotrophic factor; Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity); Belongs to the ARMET family. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.697 |
Cnpy2 | Psap | ENSMUSP00000151918 | ENSMUSP00000137476 | Protein canopy homolog 2; Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity); Belongs to the canopy family. | Saposin-B-Val; [Prosaposin]: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta- galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha- galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposins are specific low-mol [...] | 0.425 |
Cnpy2 | Psapl1 | ENSMUSP00000151918 | ENSMUSP00000100594 | Protein canopy homolog 2; Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity); Belongs to the canopy family. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.504 |
Cysrt1 | Calm4 | ENSMUSP00000140416 | ENSMUSP00000041636 | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | Calmodulin-4; Implicated in the early stage of ectopic ossification. | 0.515 |
Cysrt1 | Lce1b | ENSMUSP00000140416 | ENSMUSP00000029531 | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | Late cornified envelope 1B. | 0.525 |
Cysrt1 | Lypd3 | ENSMUSP00000140416 | ENSMUSP00000079543 | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity). | 0.567 |
Cysrt1 | Psapl1 | ENSMUSP00000140416 | ENSMUSP00000100594 | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.565 |
Krt14 | Calm4 | ENSMUSP00000007272 | ENSMUSP00000041636 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. | Calmodulin-4; Implicated in the early stage of ectopic ossification. | 0.482 |
Krt14 | Lypd3 | ENSMUSP00000007272 | ENSMUSP00000079543 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity). | 0.638 |
Krt14 | Psapl1 | ENSMUSP00000007272 | ENSMUSP00000100594 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.492 |
Lce1b | Calm4 | ENSMUSP00000029531 | ENSMUSP00000041636 | Late cornified envelope 1B. | Calmodulin-4; Implicated in the early stage of ectopic ossification. | 0.571 |
Lce1b | Cysrt1 | ENSMUSP00000029531 | ENSMUSP00000140416 | Late cornified envelope 1B. | Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. | 0.525 |
Lce1b | Psapl1 | ENSMUSP00000029531 | ENSMUSP00000100594 | Late cornified envelope 1B. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.465 |