STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc25a33Solute carrier family 25 member 33; Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and m [...] (320 aa)    
Predicted Functional Partners:
Tmem201
Transmembrane protein 201; Involved in nuclear movement during fibroblast polarization and migration. May recruit Ran GTPase to the nuclear periphery (By similarity). [Isoform 3]: Proposed to be involved in actin-dependent nuclear movement; via SUN2 associates with transmembrane actin- associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow.
 
 
  
 0.573
Slc25a53
Solute carrier family 25, member 53; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.569
Slc25a51
Solute carrier family 25 member 51.
      
 0.553
Gm16867
Predicted gene, 16867.
    
 
 0.540
Mtch1
Mitochondrial carrier homolog 1; Potential mitochondrial transporter. May play a role in apoptosis (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.517
Lzic
Protein LZIC.
   
  
 0.468
Rims2
Regulating synaptic membrane exocytosis protein 2; Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (By similarity).
   
  
 0.460
Slc45a1
Proton-associated sugar transporter A; Proton-associated glucose transporter in the brain. Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
   
  
 0.455
Lrrc47
Leucine-rich repeat-containing protein 47.
   
  
 0.428
Uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
  
  
 0.426
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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