STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc22a15Solute carrier family 22 member 15; Probably transports organic cations. Appears not to be the agmatine transporter. (544 aa)    
Predicted Functional Partners:
Slc22a18
Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
   
  
 0.670
Slc35f5
Solute carrier family 35 member F5; Putative solute transporter; Belongs to the SLC35F solute transporter family.
    
 
 0.545
Slc15a1
Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products (By similarity). Belongs to the PTR2/POT transporter (TC 2.A.17) family.
   
  
 0.506
Slc16a9
Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
      
 0.484
Slc4a8
Electroneutral sodium bicarbonate exchanger 1; Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
   
  
 0.478
Slco6c1
Solute carrier organic anion transporter family, member 6c1.
   
  
 0.470
Mab21l3
Protein mab-21-like 3; Belongs to the mab-21 family.
 
 
  
 0.470
Slc25a34
Solute carrier family 25 member 34; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.467
Slc2a9
Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose (By similarity). Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
 
 0.436
Slc2a13
Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.
  
 
 0.404
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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