node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cisd1 | Cisd3 | ENSMUSP00000043559 | ENSMUSP00000103209 | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions (By similarity). Belongs to the CISD protein family. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.802 |
Cisd2 | Cisd3 | ENSMUSP00000029815 | ENSMUSP00000103209 | CDGSH iron-sulfur domain-containing protein 2; Regulator of autophagy that contributes to antagonize BECN1- mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy (By similarity). Belongs to the CISD protein family. CISD2 subfamily. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.762 |
Cisd3 | Cisd1 | ENSMUSP00000103209 | ENSMUSP00000043559 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions (By similarity). Belongs to the CISD protein family. | 0.802 |
Cisd3 | Cisd2 | ENSMUSP00000103209 | ENSMUSP00000029815 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | CDGSH iron-sulfur domain-containing protein 2; Regulator of autophagy that contributes to antagonize BECN1- mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy (By similarity). Belongs to the CISD protein family. CISD2 subfamily. | 0.762 |
Cisd3 | Fam83c | ENSMUSP00000103209 | ENSMUSP00000029143 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.608 |
Cisd3 | Mllt6 | ENSMUSP00000103209 | ENSMUSP00000045445 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6. | 0.595 |
Cisd3 | Mrpl13 | ENSMUSP00000103209 | ENSMUSP00000130722 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 0.582 |
Cisd3 | Mrpl17 | ENSMUSP00000103209 | ENSMUSP00000117971 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 39S ribosomal protein L17, mitochondrial. | 0.754 |
Cisd3 | Mrpl24 | ENSMUSP00000103209 | ENSMUSP00000114111 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family. | 0.686 |
Cisd3 | Mrps15 | ENSMUSP00000103209 | ENSMUSP00000030675 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 28S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family. | 0.696 |
Cisd3 | Mrps16 | ENSMUSP00000103209 | ENSMUSP00000055619 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.582 |
Cisd3 | Rpl27a | ENSMUSP00000103209 | ENSMUSP00000123410 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 60S ribosomal protein L27a. | 0.627 |
Fam83c | Cisd3 | ENSMUSP00000029143 | ENSMUSP00000103209 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.608 |
Mllt6 | Cisd3 | ENSMUSP00000045445 | ENSMUSP00000103209 | Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.595 |
Mrpl13 | Cisd3 | ENSMUSP00000130722 | ENSMUSP00000103209 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.582 |
Mrpl13 | Mrpl17 | ENSMUSP00000130722 | ENSMUSP00000117971 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 39S ribosomal protein L17, mitochondrial. | 0.996 |
Mrpl13 | Mrpl24 | ENSMUSP00000130722 | ENSMUSP00000114111 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family. | 0.995 |
Mrpl13 | Mrps15 | ENSMUSP00000130722 | ENSMUSP00000030675 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 28S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family. | 0.997 |
Mrpl13 | Mrps16 | ENSMUSP00000130722 | ENSMUSP00000055619 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.997 |
Mrpl13 | Rpl27a | ENSMUSP00000130722 | ENSMUSP00000123410 | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 60S ribosomal protein L27a. | 0.551 |