node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ascl4 | Phf24 | ENSMUSP00000137650 | ENSMUSP00000103609 | Achaete-scute family bHLH transcription factor 4. | PHD finger protein 24. | 0.460 |
Dync1i1 | Phf24 | ENSMUSP00000111221 | ENSMUSP00000103609 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | PHD finger protein 24. | 0.485 |
Lancl1 | Phf24 | ENSMUSP00000109612 | ENSMUSP00000103609 | Glutathione S-transferase LANCL1; Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione (By similarity). Belongs to the LanC-like protein family. | PHD finger protein 24. | 0.467 |
Mrgprb4 | Phf24 | ENSMUSP00000091952 | ENSMUSP00000103609 | Mas-related G-protein coupled receptor member B4; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | PHD finger protein 24. | 0.454 |
Mrgprb4 | Slc17a8 | ENSMUSP00000091952 | ENSMUSP00000020102 | Mas-related G-protein coupled receptor member B4; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. | 0.483 |
Mrgprb4 | Tafa4 | ENSMUSP00000091952 | ENSMUSP00000086710 | Mas-related G-protein coupled receptor member B4; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | Chemokine-like protein TAFA-4; Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release. | 0.492 |
Mrgprd | Phf24 | ENSMUSP00000063021 | ENSMUSP00000103609 | Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity). | PHD finger protein 24. | 0.530 |
Mrgprd | Slc17a8 | ENSMUSP00000063021 | ENSMUSP00000020102 | Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity). | Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. | 0.574 |
Mrgprd | Tafa4 | ENSMUSP00000063021 | ENSMUSP00000086710 | Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity). | Chemokine-like protein TAFA-4; Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release. | 0.632 |
Pcyox1 | Phf24 | ENSMUSP00000032065 | ENSMUSP00000103609 | Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); Belongs to the prenylcysteine oxidase family. | PHD finger protein 24. | 0.476 |
Phf24 | Ascl4 | ENSMUSP00000103609 | ENSMUSP00000137650 | PHD finger protein 24. | Achaete-scute family bHLH transcription factor 4. | 0.460 |
Phf24 | Dync1i1 | ENSMUSP00000103609 | ENSMUSP00000111221 | PHD finger protein 24. | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | 0.485 |
Phf24 | Lancl1 | ENSMUSP00000103609 | ENSMUSP00000109612 | PHD finger protein 24. | Glutathione S-transferase LANCL1; Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione (By similarity). Belongs to the LanC-like protein family. | 0.467 |
Phf24 | Mrgprb4 | ENSMUSP00000103609 | ENSMUSP00000091952 | PHD finger protein 24. | Mas-related G-protein coupled receptor member B4; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | 0.454 |
Phf24 | Mrgprd | ENSMUSP00000103609 | ENSMUSP00000063021 | PHD finger protein 24. | Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity). | 0.530 |
Phf24 | Pcyox1 | ENSMUSP00000103609 | ENSMUSP00000032065 | PHD finger protein 24. | Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); Belongs to the prenylcysteine oxidase family. | 0.476 |
Phf24 | Pirt | ENSMUSP00000103609 | ENSMUSP00000128117 | PHD finger protein 24. | Phosphoinositide-interacting protein; Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI). | 0.478 |
Phf24 | Slc17a8 | ENSMUSP00000103609 | ENSMUSP00000020102 | PHD finger protein 24. | Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. | 0.458 |
Phf24 | St5 | ENSMUSP00000103609 | ENSMUSP00000077067 | PHD finger protein 24. | DENN domain-containing protein 2B; [Isoform 1]: May be involved in cytoskeletal organization and tumorogenicity. Seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Plays a role in EGFR trafficking from recycling endosomes back to the cell membrane. [Isoform 3]: May block ERK2 activation stimulated by ABL1. May alter cell morphology and cell growth. | 0.524 |
Phf24 | Tafa4 | ENSMUSP00000103609 | ENSMUSP00000086710 | PHD finger protein 24. | Chemokine-like protein TAFA-4; Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release. | 0.733 |