node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fam162b | Gpr162 | ENSMUSP00000020064 | ENSMUSP00000145267 | Protein FAM162B. | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.570 |
Fam162b | Scfd1 | ENSMUSP00000020064 | ENSMUSP00000021335 | Protein FAM162B. | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | 0.616 |
Fam162b | Tmem167 | ENSMUSP00000020064 | ENSMUSP00000125314 | Protein FAM162B. | Protein kish-A; Involved in the early part of the secretory pathway. | 0.702 |
Fam162b | Usp32 | ENSMUSP00000020064 | ENSMUSP00000103710 | Protein FAM162B. | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.633 |
Fam162b | Wdr7 | ENSMUSP00000020064 | ENSMUSP00000072509 | Protein FAM162B. | WD repeat-containing protein 7. | 0.620 |
Fam162b | Ypel5 | ENSMUSP00000020064 | ENSMUSP00000037764 | Protein FAM162B. | Protein yippee-like 5; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity). Required for normal cell proliferation (By similarity). | 0.694 |
Gpr162 | Fam162b | ENSMUSP00000145267 | ENSMUSP00000020064 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Protein FAM162B. | 0.570 |
Gpr162 | Scfd1 | ENSMUSP00000145267 | ENSMUSP00000021335 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | 0.422 |
Gpr162 | Tmem167 | ENSMUSP00000145267 | ENSMUSP00000125314 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Protein kish-A; Involved in the early part of the secretory pathway. | 0.518 |
Gpr162 | Usp32 | ENSMUSP00000145267 | ENSMUSP00000103710 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.561 |
Gpr162 | Ypel5 | ENSMUSP00000145267 | ENSMUSP00000037764 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Protein yippee-like 5; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity). Required for normal cell proliferation (By similarity). | 0.478 |
Heatr6 | Usp32 | ENSMUSP00000001002 | ENSMUSP00000103710 | HEAT repeat-containing protein 6. | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.539 |
Herc2 | Usp32 | ENSMUSP00000131573 | ENSMUSP00000103710 | E3 ubiquitin-protein ligase HERC2; E3 ubiquitin-protein ligase that regulates ubiquitin- dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in response to ionizing radiation (IR) and facilitates the assembly of UBE2N and RNF8 promoting DNA damage- induced formation of 'Lys-63'-linked ubiquitin chains. Acts as a mediator of binding specificity between UBE2N and RNF8. Involved in the maintenance of RNF168 levels. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of XPA which influences the circadian oscil [...] | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.613 |
Mysm1 | Usp14 | ENSMUSP00000075269 | ENSMUSP00000089728 | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis [...] | Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...] | 0.741 |
Mysm1 | Usp32 | ENSMUSP00000075269 | ENSMUSP00000103710 | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis [...] | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.534 |
Scfd1 | Fam162b | ENSMUSP00000021335 | ENSMUSP00000020064 | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | Protein FAM162B. | 0.616 |
Scfd1 | Gpr162 | ENSMUSP00000021335 | ENSMUSP00000145267 | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.422 |
Scfd1 | Tmem167 | ENSMUSP00000021335 | ENSMUSP00000125314 | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | Protein kish-A; Involved in the early part of the secretory pathway. | 0.670 |
Scfd1 | Usp32 | ENSMUSP00000021335 | ENSMUSP00000103710 | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family. | 0.550 |
Scfd1 | Ypel5 | ENSMUSP00000021335 | ENSMUSP00000037764 | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity); Belongs to the STXBP/unc-18/SEC1 family. | Protein yippee-like 5; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity). Required for normal cell proliferation (By similarity). | 0.465 |