node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bsph2 | Cabp5 | ENSMUSP00000104166 | ENSMUSP00000005791 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals. May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner. May play a role in the extension and network organization of neurites. | 0.663 |
Bsph2 | Catsper1 | ENSMUSP00000104166 | ENSMUSP00000045430 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. Belongs to the cation channel sperm-associated (TC 1.A.1.19) family. | 0.479 |
Bsph2 | Gas2l2 | ENSMUSP00000104166 | ENSMUSP00000051907 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.585 |
Bsph2 | Klk8 | ENSMUSP00000104166 | ENSMUSP00000082588 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Kallikrein-8; Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte [...] | 0.474 |
Bsph2 | Mrfap1 | ENSMUSP00000104166 | ENSMUSP00000067135 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | MORF4 family-associated protein 1; Belongs to the MORF4 family-associated protein family. | 0.518 |
Bsph2 | Phldb3 | ENSMUSP00000104166 | ENSMUSP00000146187 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Pleckstrin homology-like domain, family B, member 3. | 0.428 |
Bsph2 | Rnase10 | ENSMUSP00000104166 | ENSMUSP00000022424 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Inactive ribonuclease-like protein 10; Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity. | 0.489 |
Bsph2 | Tex101 | ENSMUSP00000104166 | ENSMUSP00000077150 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). | 0.457 |
Bsph2 | Wdr63 | ENSMUSP00000104166 | ENSMUSP00000124475 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | WD repeat domain 63. | 0.459 |
Bsph2 | Zfp575 | ENSMUSP00000104166 | ENSMUSP00000092294 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | Zinc finger protein 575; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.437 |
Cabp5 | Bsph2 | ENSMUSP00000005791 | ENSMUSP00000104166 | Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals. May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner. May play a role in the extension and network organization of neurites. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.663 |
Cabp5 | Phldb3 | ENSMUSP00000005791 | ENSMUSP00000146187 | Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals. May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner. May play a role in the extension and network organization of neurites. | Pleckstrin homology-like domain, family B, member 3. | 0.422 |
Catsper1 | Bsph2 | ENSMUSP00000045430 | ENSMUSP00000104166 | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. Belongs to the cation channel sperm-associated (TC 1.A.1.19) family. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.479 |
Gas2l2 | Bsph2 | ENSMUSP00000051907 | ENSMUSP00000104166 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.585 |
Klk8 | Bsph2 | ENSMUSP00000082588 | ENSMUSP00000104166 | Kallikrein-8; Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte [...] | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.474 |
Mrfap1 | Bsph2 | ENSMUSP00000067135 | ENSMUSP00000104166 | MORF4 family-associated protein 1; Belongs to the MORF4 family-associated protein family. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.518 |
Phldb3 | Bsph2 | ENSMUSP00000146187 | ENSMUSP00000104166 | Pleckstrin homology-like domain, family B, member 3. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.428 |
Phldb3 | Cabp5 | ENSMUSP00000146187 | ENSMUSP00000005791 | Pleckstrin homology-like domain, family B, member 3. | Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals. May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner. May play a role in the extension and network organization of neurites. | 0.422 |
Phldb3 | Tex101 | ENSMUSP00000146187 | ENSMUSP00000077150 | Pleckstrin homology-like domain, family B, member 3. | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). | 0.667 |
Phldb3 | Zfp575 | ENSMUSP00000146187 | ENSMUSP00000092294 | Pleckstrin homology-like domain, family B, member 3. | Zinc finger protein 575; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.736 |