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STRINGSTRING
Tshz2 protein (mouse) - STRING interaction network
"Tshz2" - Teashirt homolog 2 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tshz2Teashirt homolog 2; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential) (1030 aa)    
Predicted Functional Partners:
Zfp217
Zinc finger protein 217 (1041 aa)
       
 
  0.649
Meis2
Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform Meis2B is required for the activity of a PDX1-PBX1b-MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probab [...] (477 aa)
     
 
  0.633
Adap1
ArfGAP with dual PH domains 1 (374 aa)
           
  0.609
Meis1
Homeobox protein Meis1; Acts as a transcriptional regulator of PAX6. Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias; Belongs to the TALE/MEIS homeobox family (465 aa)
     
 
  0.595
Zfp64
Zinc finger protein 64 (676 aa)
       
 
  0.585
Zfp503
Zinc finger protein 503; May function as a transcriptional repressor (652 aa)
     
   
  0.549
Cog3
Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport (828 aa)
           
  0.543
Parm1
Prostate androgen-regulated mucin-like protein 1 homolog; May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis (296 aa)
     
   
  0.540
Gm12695
Uncharacterized protein C1orf87 homolog; Predicted gene 12695 (545 aa)
           
  0.537
Lix1l
Lix1-like; Belongs to the LIX1 family (337 aa)
           
  0.529
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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