STRINGSTRING
Vstm2a protein (mouse) - STRING interaction network
"Vstm2a" - V-set and transmembrane domain-containing protein 2A in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vstm2aV-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway (236 aa)    
Predicted Functional Partners:
Pnmal1
Paraneoplastic antigen-like protein 8A; PNMA-like 1; Belongs to the PNMA family (430 aa)
     
   
  0.686
Lonrf2
LON peptidase N-terminal domain and ring finger 2 (518 aa)
     
   
  0.679
Sumf2
Sulfatase-modifying factor 2; Lacks formyl-glycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1 (By similarity) (308 aa)
           
  0.654
Pgbd5
PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements (523 aa)
     
   
  0.645
Sept14
Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential) (430 aa)
           
  0.623
Sult4a1
Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3’-phospho-5’-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS (284 aa)
     
   
  0.622
Fam155a
Transmembrane protein FAM155A; Family with sequence similarity 155, member A; Belongs to the FAM155 family (467 aa)
     
   
  0.620
Lancl2
LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes; Belongs to the LanC-like protein family (450 aa)
     
   
  0.617
Map7d2
MAP7 domain containing 2 (781 aa)
     
   
  0.606
Sec61g
Protein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum (100 aa)
           
  0.579
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (8%) [HD]