STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb20Beta-defensin 20; Has antibacterial activity; Belongs to the beta-defensin family. (96 aa)    
Predicted Functional Partners:
Defb23
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.758
Defb18
Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.738
Defb22
Beta-defensin 22; Probable component of sperm glycocalyx. Likely protects and facilitates transport of sperm in the female reproductive tract. Probably released from the sperm surface during capacitation. Belongs to the beta-defensin family.
   
  
 0.710
Defb45
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.707
Defb30
Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.673
Defb28
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.664
Defb25
Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.661
Defb42
Beta-defensin 42; Has bactericidal activity (By similarity). May play a role in the antimicrobial protection of sperm and urogenital tract epithelia ; Belongs to the beta-defensin family.
      
 0.656
Defb21
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.633
Defb10
Beta-defensin 10; Has antibacterial activity.
   
  
 0.560
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.