STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fam110aProtein FAM110A; Belongs to the FAM110 family. (296 aa)    
Predicted Functional Partners:
Tm2d2
TM2 domain-containing protein 2.
   
  
 0.690
Zmat4
Zinc finger matrin-type protein 4.
      
 0.599
Rogdi
Protein rogdi homolog; Belongs to the rogdi family.
      
 0.598
Kctd3
BTB/POZ domain-containing protein KCTD3; Accessory subunit of potassium/sodium hyperpolarization- activated cyclic nucleotide-gated channel 3 (HCN3) upregulating its cell-surface expression and current density without affecting its voltage dependence and kinetics.
      
 0.546
Gpank1
G patch domain and ankyrin repeat-containing protein 1.
   
  
 0.542
Olfr522
Olfactory receptor.
      
 0.538
Zdhhc18
Palmitoyltransferase ZDHHC18; Has palmitoyltransferase activity towards HRAS and LCK.
   
  
 0.537
Csnk1e
Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
   
 
 0.536
Golt1b
Vesicle transport protein GOT1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family.
      
 0.523
Ankrd9
Ankyrin repeat domain-containing protein 9.
   
  
 0.511
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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