node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cabp7 | Smoc1 | ENSMUSP00000009219 | ENSMUSP00000105976 | Calcium-binding protein 7; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.580 |
Clec3b | Smoc1 | ENSMUSP00000026890 | ENSMUSP00000105976 | Tetranectin; Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis (By similarity). | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.564 |
Fkbp10 | Smoc1 | ENSMUSP00000001595 | ENSMUSP00000105976 | Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.537 |
Jade1 | Sfmbt2 | ENSMUSP00000128152 | ENSMUSP00000040575 | Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (By similarity). Belongs to the JADE family. | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | 0.710 |
Jade1 | Slc38a4 | ENSMUSP00000128152 | ENSMUSP00000023101 | Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (By similarity). Belongs to the JADE family. | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | 0.571 |
Jade1 | Smoc1 | ENSMUSP00000128152 | ENSMUSP00000105976 | Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (By similarity). Belongs to the JADE family. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.642 |
Lgi2 | Smoc1 | ENSMUSP00000040436 | ENSMUSP00000105976 | Leucine-rich repeat LGI family member 2; Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.538 |
Nap1l5 | Sfmbt2 | ENSMUSP00000062780 | ENSMUSP00000040575 | Nucleosome assembly protein 1-like 5. | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | 0.527 |
Nap1l5 | Slc38a4 | ENSMUSP00000062780 | ENSMUSP00000023101 | Nucleosome assembly protein 1-like 5. | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | 0.552 |
Nap1l5 | Smoc1 | ENSMUSP00000062780 | ENSMUSP00000105976 | Nucleosome assembly protein 1-like 5. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.546 |
Sall1 | Smoc1 | ENSMUSP00000034090 | ENSMUSP00000105976 | Sal-like protein 1; Transcriptional repressor involved in organogenesis. Essential for ureteric bud invasion in kidney development. Homozygous deletion of SALL1 results in an incomplete ureteric bud outgrowth, a failure of tubule formation in the mesenchyme and an apoptosis of the mesenchyme; Belongs to the sal C2H2-type zinc-finger protein family. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.566 |
Sfmbt2 | Jade1 | ENSMUSP00000040575 | ENSMUSP00000128152 | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (By similarity). Belongs to the JADE family. | 0.710 |
Sfmbt2 | Nap1l5 | ENSMUSP00000040575 | ENSMUSP00000062780 | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | Nucleosome assembly protein 1-like 5. | 0.527 |
Sfmbt2 | Slc38a4 | ENSMUSP00000040575 | ENSMUSP00000023101 | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | 0.808 |
Sfmbt2 | Smoc1 | ENSMUSP00000040575 | ENSMUSP00000105976 | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.689 |
Slc38a4 | Jade1 | ENSMUSP00000023101 | ENSMUSP00000128152 | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (By similarity). Belongs to the JADE family. | 0.571 |
Slc38a4 | Nap1l5 | ENSMUSP00000023101 | ENSMUSP00000062780 | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | Nucleosome assembly protein 1-like 5. | 0.552 |
Slc38a4 | Sfmbt2 | ENSMUSP00000023101 | ENSMUSP00000040575 | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene. | 0.808 |
Slc38a4 | Smoc1 | ENSMUSP00000023101 | ENSMUSP00000105976 | Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5. Belongs to the amino acid/polyamine transporter 2 family. | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | 0.721 |
Smoc1 | Cabp7 | ENSMUSP00000105976 | ENSMUSP00000009219 | SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. | Calcium-binding protein 7; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. | 0.580 |