STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spata17Spermatogenesis-associated protein 17. (379 aa)    
Predicted Functional Partners:
Spata4
Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.
   
  
 0.746
Spata31d1d
Spermatogenesis-associated 31 subfamily D, member 1D.
   
 
 0.712
Nudt16l2
Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2.
   
  
 0.664
Spata7
Spermatogenesis-associated protein 7 homolog; Involved in the maintenance of both rod and cone photoreceptor cells. Required for photoreceptor-specific localization of proximal connecting cilium (CC) proteins RPGR, AHI1, NPHP1, NPHP4, and RPGRIP1 at the distal CC, a photoreceptor-specific extension of the primary cilium transition zone. Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration.
   
  
 0.647
Gpatch2
G patch domain-containing protein 2; Enhances the ATPase activity of DHX15 in vitro.
      
 0.633
Rrp15
RRP15-like protein.
      
 0.631
Spag17
Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts.
   
 
 0.630
Spata20
Spermatogenesis-associated protein 20; May play a role in fertility regulation.
   
  
 0.623
Lrguk
Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.
   
 
 0.614
Tex48
Testis-expressed 48.
   
  
 0.610
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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