node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clec18a | Ssc4d | ENSMUSP00000046546 | ENSMUSP00000106782 | C-type lectin domain family 18 member A. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.485 |
Dclre1a | Ssc4d | ENSMUSP00000138290 | ENSMUSP00000106782 | DNA cross-link repair 1A protein; May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.425 |
Fat3 | Ssc4d | ENSMUSP00000080808 | ENSMUSP00000106782 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.499 |
Fbln1 | Fbxo21 | ENSMUSP00000054583 | ENSMUSP00000143873 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. | 0.436 |
Fbln1 | Lox | ENSMUSP00000054583 | ENSMUSP00000025409 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. | 0.522 |
Fbln1 | Ssc4d | ENSMUSP00000054583 | ENSMUSP00000106782 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.533 |
Fbxo21 | Fbln1 | ENSMUSP00000143873 | ENSMUSP00000054583 | F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | 0.436 |
Fbxo21 | Ssc4d | ENSMUSP00000143873 | ENSMUSP00000106782 | F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.588 |
Hoga1 | Ssc4d | ENSMUSP00000080414 | ENSMUSP00000106782 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.435 |
Lox | Fbln1 | ENSMUSP00000025409 | ENSMUSP00000054583 | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | 0.522 |
Lox | Ssc4d | ENSMUSP00000025409 | ENSMUSP00000106782 | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.504 |
Srd5a3 | Ssc4d | ENSMUSP00000031143 | ENSMUSP00000106782 | Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5- alpha-dihydrotestosterone (DHT). | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.433 |
Ssc4d | Clec18a | ENSMUSP00000106782 | ENSMUSP00000046546 | Scavenger receptor cysteine-rich domain-containing group B protein. | C-type lectin domain family 18 member A. | 0.485 |
Ssc4d | Dclre1a | ENSMUSP00000106782 | ENSMUSP00000138290 | Scavenger receptor cysteine-rich domain-containing group B protein. | DNA cross-link repair 1A protein; May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. | 0.425 |
Ssc4d | Fat3 | ENSMUSP00000106782 | ENSMUSP00000080808 | Scavenger receptor cysteine-rich domain-containing group B protein. | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.499 |
Ssc4d | Fbln1 | ENSMUSP00000106782 | ENSMUSP00000054583 | Scavenger receptor cysteine-rich domain-containing group B protein. | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. | 0.533 |
Ssc4d | Fbxo21 | ENSMUSP00000106782 | ENSMUSP00000143873 | Scavenger receptor cysteine-rich domain-containing group B protein. | F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. | 0.588 |
Ssc4d | Hoga1 | ENSMUSP00000106782 | ENSMUSP00000080414 | Scavenger receptor cysteine-rich domain-containing group B protein. | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline. | 0.435 |
Ssc4d | Lox | ENSMUSP00000106782 | ENSMUSP00000025409 | Scavenger receptor cysteine-rich domain-containing group B protein. | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. | 0.504 |
Ssc4d | Srd5a3 | ENSMUSP00000106782 | ENSMUSP00000031143 | Scavenger receptor cysteine-rich domain-containing group B protein. | Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5- alpha-dihydrotestosterone (DHT). | 0.433 |