STRINGSTRING
Zfp664 protein (mouse) - STRING interaction network
"Zfp664" - Zinc finger protein 664 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zfp664Zinc finger protein 664; May be involved in transcriptional regulation (261 aa)    
Predicted Functional Partners:
Trim28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (834 aa)
     
    0.903
Dnah10
Dynein, axonemal, heavy chain 10 (4591 aa)
       
 
  0.699
Nt5dc2
5’-nucleotidase domain containing 2 (390 aa)
       
 
  0.645
Arl15
ADP-ribosylation factor-like 15; Belongs to the small GTPase superfamily. Arf family (204 aa)
       
 
  0.628
Ccdc92
Coiled-coil domain containing 92 (314 aa)
           
  0.624
Trib1
Tribbles homolog 1; Adapter protein involved in protein degradation by interacting with RFWD2/COP1 ubiquitin ligase. Promotes CEBPA degradation and inhibits its function. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain. Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1- dependent manner. Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily (372 aa)
     
 
  0.594
Cmip
C-Maf-inducing protein; Plays a role in T-cell signaling pathway (773 aa)
           
  0.586
Tsc22d2
TSC22 domain family, member 2 (769 aa)
       
 
  0.585
Ccdc121
Coiled-coil domain containing 121 (323 aa)
           
  0.571
Btnl2
Butyrophilin-like protein 2; Negative regulator of T-cell proliferation; Belongs to the immunoglobulin superfamily. BTN/MOG family (514 aa)
           
  0.567
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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