node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Afap1l2 | Asap2 | ENSMUSP00000107210 | ENSMUSP00000063217 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | 0.449 |
Afap1l2 | Ccdc186 | ENSMUSP00000107210 | ENSMUSP00000113457 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Coiled-coil domain-containing protein 186. | 0.467 |
Afap1l2 | Cdadc1 | ENSMUSP00000107210 | ENSMUSP00000153357 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | 0.428 |
Afap1l2 | Clmn | ENSMUSP00000107210 | ENSMUSP00000105563 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Calmin. | 0.489 |
Afap1l2 | Dnlz | ENSMUSP00000107210 | ENSMUSP00000028295 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | DNL-type zinc finger protein; May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation. | 0.484 |
Afap1l2 | Lpgat1 | ENSMUSP00000107210 | ENSMUSP00000106480 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl- CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor (By similarity). | 0.438 |
Afap1l2 | Nhlrc2 | ENSMUSP00000107210 | ENSMUSP00000071370 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | NHL repeat-containing protein 2; Required for normal embryonic development. | 0.433 |
Afap1l2 | Pi16 | ENSMUSP00000107210 | ENSMUSP00000110349 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Peptidase inhibitor 16; May inhibit cardiomyocyte growth. | 0.444 |
Afap1l2 | Ptpn14 | ENSMUSP00000107210 | ENSMUSP00000095051 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Tyrosine-protein phosphatase non-receptor type 14; Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. | 0.476 |
Afap1l2 | Tacc2 | ENSMUSP00000107210 | ENSMUSP00000081561 | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | Transforming acidic coiled-coil-containing protein 2; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules (By similarity). | 0.467 |
Asap2 | Afap1l2 | ENSMUSP00000063217 | ENSMUSP00000107210 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.449 |
Ccdc186 | Afap1l2 | ENSMUSP00000113457 | ENSMUSP00000107210 | Coiled-coil domain-containing protein 186. | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.467 |
Ccdc186 | Cdadc1 | ENSMUSP00000113457 | ENSMUSP00000153357 | Coiled-coil domain-containing protein 186. | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | 0.546 |
Ccdc186 | Nhlrc2 | ENSMUSP00000113457 | ENSMUSP00000071370 | Coiled-coil domain-containing protein 186. | NHL repeat-containing protein 2; Required for normal embryonic development. | 0.654 |
Cdadc1 | Afap1l2 | ENSMUSP00000153357 | ENSMUSP00000107210 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.428 |
Cdadc1 | Ccdc186 | ENSMUSP00000153357 | ENSMUSP00000113457 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | Coiled-coil domain-containing protein 186. | 0.546 |
Cdadc1 | Nhlrc2 | ENSMUSP00000153357 | ENSMUSP00000071370 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | NHL repeat-containing protein 2; Required for normal embryonic development. | 0.497 |
Clmn | Afap1l2 | ENSMUSP00000105563 | ENSMUSP00000107210 | Calmin. | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.489 |
Dnlz | Afap1l2 | ENSMUSP00000028295 | ENSMUSP00000107210 | DNL-type zinc finger protein; May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation. | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.484 |
Lpgat1 | Afap1l2 | ENSMUSP00000106480 | ENSMUSP00000107210 | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl- CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor (By similarity). | Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity). | 0.438 |