node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2900026A02Rik | Styx | ENSMUSP00000148442 | ENSMUSP00000153854 | Uncharacterized protein KIAA1671. | Serine/threonine/tyrosine interaction protein. | 0.418 |
Acp1 | Styx | ENSMUSP00000106509 | ENSMUSP00000153854 | Low molecular weight phosphotyrosine protein phosphatase; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. | Serine/threonine/tyrosine interaction protein. | 0.433 |
Carhsp1 | Styx | ENSMUSP00000008537 | ENSMUSP00000153854 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Serine/threonine/tyrosine interaction protein. | 0.521 |
Ddhd1 | Gpr137c | ENSMUSP00000084577 | ENSMUSP00000120015 | Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Required for the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (By similarity). Belongs to the PA-PLA1 family. | G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. | 0.537 |
Ddhd1 | Styx | ENSMUSP00000084577 | ENSMUSP00000153854 | Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Required for the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (By similarity). Belongs to the PA-PLA1 family. | Serine/threonine/tyrosine interaction protein. | 0.412 |
Ddhd1 | Txndc16 | ENSMUSP00000084577 | ENSMUSP00000120287 | Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Required for the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (By similarity). Belongs to the PA-PLA1 family. | Thioredoxin domain-containing protein 16. | 0.602 |
Fbxw7 | Styx | ENSMUSP00000103306 | ENSMUSP00000153854 | F-box/WD repeat-containing protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Mediates ubiquitination and subsequent degradation of CCNE1 and MYC. Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NOTCH2, MCL1 and pr [...] | Serine/threonine/tyrosine interaction protein. | 0.401 |
Gnpnat1 | Styx | ENSMUSP00000042860 | ENSMUSP00000153854 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | Serine/threonine/tyrosine interaction protein. | 0.411 |
Gpr137c | Ddhd1 | ENSMUSP00000120015 | ENSMUSP00000084577 | G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. | Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Required for the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (By similarity). Belongs to the PA-PLA1 family. | 0.537 |
Gpr137c | Styx | ENSMUSP00000120015 | ENSMUSP00000153854 | G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. | Serine/threonine/tyrosine interaction protein. | 0.511 |
Gpr137c | Txndc16 | ENSMUSP00000120015 | ENSMUSP00000120287 | G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. | Thioredoxin domain-containing protein 16. | 0.667 |
Retreg3 | Styx | ENSMUSP00000017946 | ENSMUSP00000153854 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth. Belongs to the RETREG family. | Serine/threonine/tyrosine interaction protein. | 0.411 |
Shoc2 | Styx | ENSMUSP00000025932 | ENSMUSP00000153854 | Leucine-rich repeat protein SHOC-2; Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. | Serine/threonine/tyrosine interaction protein. | 0.416 |
Styx | 2900026A02Rik | ENSMUSP00000153854 | ENSMUSP00000148442 | Serine/threonine/tyrosine interaction protein. | Uncharacterized protein KIAA1671. | 0.418 |
Styx | Acp1 | ENSMUSP00000153854 | ENSMUSP00000106509 | Serine/threonine/tyrosine interaction protein. | Low molecular weight phosphotyrosine protein phosphatase; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. | 0.433 |
Styx | Carhsp1 | ENSMUSP00000153854 | ENSMUSP00000008537 | Serine/threonine/tyrosine interaction protein. | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.521 |
Styx | Ddhd1 | ENSMUSP00000153854 | ENSMUSP00000084577 | Serine/threonine/tyrosine interaction protein. | Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Required for the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (By similarity). Belongs to the PA-PLA1 family. | 0.412 |
Styx | Fbxw7 | ENSMUSP00000153854 | ENSMUSP00000103306 | Serine/threonine/tyrosine interaction protein. | F-box/WD repeat-containing protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Mediates ubiquitination and subsequent degradation of CCNE1 and MYC. Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NOTCH2, MCL1 and pr [...] | 0.401 |
Styx | Gnpnat1 | ENSMUSP00000153854 | ENSMUSP00000042860 | Serine/threonine/tyrosine interaction protein. | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | 0.411 |
Styx | Gpr137c | ENSMUSP00000153854 | ENSMUSP00000120015 | Serine/threonine/tyrosine interaction protein. | G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. | 0.511 |