node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alpi | Gch1 | ENSMUSP00000108895 | ENSMUSP00000087405 | Alkaline phosphatase. | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence. | 0.901 |
Alpi | Ggt5 | ENSMUSP00000108895 | ENSMUSP00000072074 | Alkaline phosphatase. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.598 |
Alpi | Ggt6 | ENSMUSP00000108895 | ENSMUSP00000075773 | Alkaline phosphatase. | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | 0.670 |
Alpi | Ggt7 | ENSMUSP00000108895 | ENSMUSP00000029131 | Alkaline phosphatase. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.653 |
Alpi | Got1 | ENSMUSP00000108895 | ENSMUSP00000026196 | Alkaline phosphatase. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.661 |
Alpi | Got1l1 | ENSMUSP00000108895 | ENSMUSP00000041337 | Alkaline phosphatase. | Putative aspartate aminotransferase, cytoplasmic 2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.662 |
Alpi | Muc2 | ENSMUSP00000108895 | ENSMUSP00000141128 | Alkaline phosphatase. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.553 |
Alpi | Ntpcr | ENSMUSP00000108895 | ENSMUSP00000034313 | Alkaline phosphatase. | Cancer-related nucleoside-triphosphatase homolog; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency (By similarity). | 0.900 |
Alpi | Pts | ENSMUSP00000108895 | ENSMUSP00000034570 | Alkaline phosphatase. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. | 0.900 |
Alpi | Tpk1 | ENSMUSP00000108895 | ENSMUSP00000065631 | Alkaline phosphatase. | Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate. | 0.907 |
Gch1 | Alpi | ENSMUSP00000087405 | ENSMUSP00000108895 | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence. | Alkaline phosphatase. | 0.901 |
Gch1 | Pts | ENSMUSP00000087405 | ENSMUSP00000034570 | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. | 0.985 |
Ggt5 | Alpi | ENSMUSP00000072074 | ENSMUSP00000108895 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Alkaline phosphatase. | 0.598 |
Ggt5 | Ggt6 | ENSMUSP00000072074 | ENSMUSP00000075773 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | 0.961 |
Ggt5 | Ggt7 | ENSMUSP00000072074 | ENSMUSP00000029131 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.957 |
Ggt5 | Got1 | ENSMUSP00000072074 | ENSMUSP00000026196 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.463 |
Ggt5 | Got1l1 | ENSMUSP00000072074 | ENSMUSP00000041337 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Putative aspartate aminotransferase, cytoplasmic 2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.489 |
Ggt6 | Alpi | ENSMUSP00000075773 | ENSMUSP00000108895 | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | Alkaline phosphatase. | 0.670 |
Ggt6 | Ggt5 | ENSMUSP00000075773 | ENSMUSP00000072074 | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.961 |
Ggt6 | Ggt7 | ENSMUSP00000075773 | ENSMUSP00000029131 | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.934 |