STRINGSTRING
Prdm12 protein (mouse) - STRING interaction network
"Prdm12" - PR domain zinc finger protein 12 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
Prdm12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation (365 aa)    
Predicted Functional Partners:
Evx1
Homeobox even-skipped homolog protein 1; May play a role in the specification of neuronal cell types. May play a role in the dorsoventral specification of mesodermal cell fate (416 aa)
           
  0.662
Hmcn2
Hemicentin-2; Hemicentin 2 (5100 aa)
           
  0.571
En1
Homeobox protein engrailed-1; Engrailed 1 (401 aa)
     
   
  0.556
Mageb4
Melanoma-associated antigen B4; Melanoma antigen, family B, 4 (556 aa)
           
  0.554
Dbx1
Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (335 aa)
     
   
  0.550
Dbx2
Developing brain homeobox 2 (377 aa)
           
  0.539
Fndc3a
Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis (1198 aa)
           
  0.538
Setmar
Histone-lysine N-methyltransferase SETMAR; Histone methyltransferase that methylates ’Lys-4’ and ’Lys-36’ of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 ’Lys-36’; Belongs to the class V-like SAM-binding methyltransferase superfamily (309 aa)
       
 
  0.536
Olfr323
Olfactory receptor 323 (323 aa)
           
  0.519
Ormdl1
ORM1-like protein 1; Negative regulator of sphingolipid synthesis (153 aa)
           
  0.475
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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