node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adad2 | Fbxo47 | ENSMUSP00000095964 | ENSMUSP00000091471 | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.447 |
Adad2 | M1ap | ENSMUSP00000095964 | ENSMUSP00000109613 | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | 0.570 |
Adad2 | Meioc | ENSMUSP00000095964 | ENSMUSP00000097947 | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | Meiosis-specific coiled-coil domain-containing protein MEIOC; Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. | 0.408 |
Adad2 | Shoc1 | ENSMUSP00000095964 | ENSMUSP00000103171 | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | Protein shortage in chiasmata 1 ortholog; ATPase required during meiosis for the formation of crossover recombination intermediates. Binds DNA: preferentially binds to single-stranded DNA and DNA branched structures (By similarity). Does not show nuclease activity in vitro, but shows ATPase activity, which is stimulated by the presence of single-stranded DNA (By similarity). | 0.665 |
D630039A03Rik | M1ap | ENSMUSP00000068932 | ENSMUSP00000109613 | RIKEN cDNA D630039A03 gene. | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | 0.572 |
D630039A03Rik | Smc1b | ENSMUSP00000068932 | ENSMUSP00000023068 | RIKEN cDNA D630039A03 gene. | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | 0.410 |
Fbxo47 | Adad2 | ENSMUSP00000091471 | ENSMUSP00000095964 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | 0.447 |
Fbxo47 | M1ap | ENSMUSP00000091471 | ENSMUSP00000109613 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | 0.656 |
M1ap | Adad2 | ENSMUSP00000109613 | ENSMUSP00000095964 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family. | 0.570 |
M1ap | D630039A03Rik | ENSMUSP00000109613 | ENSMUSP00000068932 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | RIKEN cDNA D630039A03 gene. | 0.572 |
M1ap | Fbxo47 | ENSMUSP00000109613 | ENSMUSP00000091471 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.656 |
M1ap | Mei1 | ENSMUSP00000109613 | ENSMUSP00000140479 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes. | 0.605 |
M1ap | Meioc | ENSMUSP00000109613 | ENSMUSP00000097947 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Meiosis-specific coiled-coil domain-containing protein MEIOC; Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. | 0.618 |
M1ap | Shoc1 | ENSMUSP00000109613 | ENSMUSP00000103171 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Protein shortage in chiasmata 1 ortholog; ATPase required during meiosis for the formation of crossover recombination intermediates. Binds DNA: preferentially binds to single-stranded DNA and DNA branched structures (By similarity). Does not show nuclease activity in vitro, but shows ATPase activity, which is stimulated by the presence of single-stranded DNA (By similarity). | 0.635 |
M1ap | Smc1b | ENSMUSP00000109613 | ENSMUSP00000023068 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | 0.499 |
M1ap | Stag3 | ENSMUSP00000109613 | ENSMUSP00000040945 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Cohesin subunit SA-3; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I; Belongs to the SCC3 family. | 0.621 |
M1ap | Stpg2 | ENSMUSP00000109613 | ENSMUSP00000051539 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Sperm-tail PG-rich repeat-containing protein 2. | 0.665 |
M1ap | Sycp2 | ENSMUSP00000109613 | ENSMUSP00000079909 | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | Synaptonemal complex protein 2; Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. Belongs [...] | 0.552 |
Mei1 | M1ap | ENSMUSP00000140479 | ENSMUSP00000109613 | Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes. | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | 0.605 |
Mei1 | Meioc | ENSMUSP00000140479 | ENSMUSP00000097947 | Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes. | Meiosis-specific coiled-coil domain-containing protein MEIOC; Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. | 0.597 |