STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Colca2COLCA2 homolog. (239 aa)    
Predicted Functional Partners:
1810046K07Rik
Uncharacterized protein C11orf53 homolog.
  
   
 0.802
1110032A03Rik
UPF0686 protein C11orf1 homolog; Belongs to the UPF0686 family.
      
 0.555
Plekhd1
Pleckstrin homology domain-containing family D member 1; Belongs to the PLEKHD1 family.
      
 0.491
Wbp1l
WW domain binding protein 1-like.
      
 0.468
Rlf
Rearranged L-myc fusion sequence.
      
 0.465
Map7d2
MAP7 domain-containing protein 2.
      
 0.461
Syce3
Synaptonemal complex central element protein 3; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. May play a role in apoptosis of spermatogenic cells and pathogenesis of cryptorchidism.
  
     0.456
Higd1a
HIG1 domain family member 1A, mitochondrial; Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes (By similarity).
      
 0.445
Zswim5
Zinc finger SWIM domain-containing protein 5.
      
 0.432
Nrsn1
Neurensin-1; May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.
      
 0.416
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.