STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adgrf3Adhesion G-protein coupled receptor F3; Orphan receptor. (991 aa)    
Predicted Functional Partners:
Cd164l2
CD164 sialomucin-like 2 protein.
      
 0.750
Adgrg4
Adhesion G-protein coupled receptor G4; Orphan receptor.
      
 0.603
Adgra1
Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
    
 
 0.547
Adgra3
Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway.
    
 
 0.545
Olfr574
Olfactory receptor.
      
 0.538
Trcg1
Taste receptor cell protein 1.
   
  
 0.486
Olfr1033
Olfactory receptor.
      
 0.463
Gprc5d
G-protein coupled receptor family C group 5 member D; Belongs to the G-protein coupled receptor 3 family.
      
 0.459
Adgrv1
Adhesion G-protein coupled receptor V1; G-protein coupled receptor which has an essential role in the development of hearing and vision. Couples to G-alpha(i)-proteins, GNAI1/2/3, G-alpha(q)-proteins, GNAQ, as well as G-alpha(s)-proteins, GNAS, inhibiting adenylate cyclase (AC) activity and cAMP production. Required for the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells of the inner ear. In response to extracellular calcium, activates kinases PKA and PKC to regulate myelination by inhibiting the ubiquitination of MAG, thus enhancing th [...]
      
 0.441
Gtf2e2
General transcription factor IIE subunit 2; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity). Belongs to the TFIIE beta subunit family.
      
 0.420
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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