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Uhrf1bp1 protein (mouse) - STRING interaction network
"Uhrf1bp1" - UHRF1 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Uhrf1bp1UHRF1 (ICBP90) binding protein 1 (1429 aa)    
Predicted Functional Partners:
Snrpc
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5’ splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5’ splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5’ splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5’ end of the U1 snRNA and the 5’ splice-site region (159 aa)
           
  0.702
Anks1
Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (1150 aa)
     
 
  0.664
Wdfy4
WD repeat and FYVE domain containing 4 (3149 aa)
     
   
  0.661
Zfp523
Zinc finger protein 76; May be involved in transcriptional regulation (568 aa)
           
  0.647
Zfp758
Zinc finger protein 758 (583 aa)
           
  0.639
Zfp943
Zinc finger prtoein 943 (507 aa)
           
  0.639
Anks1b
Ankyrin repeat and sterile alpha motif domain-containing protein 1B; Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells (1259 aa)
       
 
  0.619
Morc1
MORC family CW-type zinc finger protein 1; Required for spermatogenesis (950 aa)
           
  0.603
Supt5
Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...] (1082 aa)
           
  0.603
Xkr6
XK-related protein 6; X Kell blood group precursor related family member 6 homolog; Belongs to the XK family (638 aa)
           
  0.571
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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