node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ahsg | Bglap | ENSMUSP00000023583 | ENSMUSP00000075425 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.495 |
Ahsg | Bglap2 | ENSMUSP00000023583 | ENSMUSP00000096555 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.492 |
Ahsg | Bglap3 | ENSMUSP00000023583 | ENSMUSP00000103166 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 0.489 |
Ahsg | Ggcx | ENSMUSP00000023583 | ENSMUSP00000070109 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.424 |
Ahsg | Mgp | ENSMUSP00000023583 | ENSMUSP00000032342 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. | 0.956 |
Ahsg | Runx2 | ENSMUSP00000023583 | ENSMUSP00000109201 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation (By similarity). In osteoblasts, supports transc [...] | 0.486 |
Ahsg | Ucma | ENSMUSP00000023583 | ENSMUSP00000110662 | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family. | 0.576 |
Bglap | Ahsg | ENSMUSP00000075425 | ENSMUSP00000023583 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | 0.495 |
Bglap | Bglap2 | ENSMUSP00000075425 | ENSMUSP00000096555 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.980 |
Bglap | Bglap3 | ENSMUSP00000075425 | ENSMUSP00000103166 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap | Ggcx | ENSMUSP00000075425 | ENSMUSP00000070109 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.688 |
Bglap | Mgp | ENSMUSP00000075425 | ENSMUSP00000032342 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. | 0.867 |
Bglap | Pros1 | ENSMUSP00000075425 | ENSMUSP00000023629 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.541 |
Bglap | Runx2 | ENSMUSP00000075425 | ENSMUSP00000109201 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation (By similarity). In osteoblasts, supports transc [...] | 0.980 |
Bglap | Sp7 | ENSMUSP00000075425 | ENSMUSP00000077596 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Transcription factor Sp7; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences. Belongs to the Sp1 C2H2-type zinc-finger protein family. | 0.882 |
Bglap | Ucma | ENSMUSP00000075425 | ENSMUSP00000110662 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family. | 0.534 |
Bglap2 | Ahsg | ENSMUSP00000096555 | ENSMUSP00000023583 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family. | 0.492 |
Bglap2 | Bglap | ENSMUSP00000096555 | ENSMUSP00000075425 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.980 |
Bglap2 | Bglap3 | ENSMUSP00000096555 | ENSMUSP00000103166 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap2 | Ggcx | ENSMUSP00000096555 | ENSMUSP00000070109 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.918 |