node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agbl3 | Gspt2 | ENSMUSP00000110668 | ENSMUSP00000109523 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). | 0.477 |
Agbl3 | Nudt16l2 | ENSMUSP00000110668 | ENSMUSP00000035180 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | 0.676 |
Agbl3 | Rhobtb3 | ENSMUSP00000110668 | ENSMUSP00000022078 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Rho-related BTB domain-containing protein 3; Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9 (By similarity). | 0.470 |
Agbl3 | Spata31d1d | ENSMUSP00000110668 | ENSMUSP00000128200 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Spermatogenesis-associated 31 subfamily D, member 1D. | 0.700 |
Agbl3 | Svopl | ENSMUSP00000110668 | ENSMUSP00000093743 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Putative transporter SVOPL; Belongs to the major facilitator superfamily. | 0.477 |
Agbl3 | Tex22 | ENSMUSP00000110668 | ENSMUSP00000012355 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Testis-expressed protein 22. | 0.478 |
Agbl3 | Tex48 | ENSMUSP00000110668 | ENSMUSP00000099925 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Testis-expressed 48. | 0.641 |
Agbl3 | Tmco5 | ENSMUSP00000110668 | ENSMUSP00000028834 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Transmembrane and coiled-coil domain-containing protein 5A; Belongs to the TMCO5 family. | 0.476 |
Agbl3 | Ttll13 | ENSMUSP00000110668 | ENSMUSP00000062795 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Tubulin polyglutamylase TTLL13; Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. | 0.493 |
Agbl3 | Zc3h12c | ENSMUSP00000110668 | ENSMUSP00000127603 | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | Probable ribonuclease ZC3H12C; May function as RNase and regulate the levels of target RNA species. | 0.452 |
Gspt2 | Agbl3 | ENSMUSP00000109523 | ENSMUSP00000110668 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | 0.477 |
Nudt16l2 | Agbl3 | ENSMUSP00000035180 | ENSMUSP00000110668 | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | 0.676 |
Nudt16l2 | Spata31d1d | ENSMUSP00000035180 | ENSMUSP00000128200 | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | Spermatogenesis-associated 31 subfamily D, member 1D. | 0.891 |
Nudt16l2 | Tex48 | ENSMUSP00000035180 | ENSMUSP00000099925 | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | Testis-expressed 48. | 0.862 |
Nudt16l2 | Tmco5 | ENSMUSP00000035180 | ENSMUSP00000028834 | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | Transmembrane and coiled-coil domain-containing protein 5A; Belongs to the TMCO5 family. | 0.708 |
Rhobtb3 | Agbl3 | ENSMUSP00000022078 | ENSMUSP00000110668 | Rho-related BTB domain-containing protein 3; Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9 (By similarity). | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | 0.470 |
Spata31d1d | Agbl3 | ENSMUSP00000128200 | ENSMUSP00000110668 | Spermatogenesis-associated 31 subfamily D, member 1D. | Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. | 0.700 |
Spata31d1d | Nudt16l2 | ENSMUSP00000128200 | ENSMUSP00000035180 | Spermatogenesis-associated 31 subfamily D, member 1D. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2. | 0.891 |
Spata31d1d | Tex48 | ENSMUSP00000128200 | ENSMUSP00000099925 | Spermatogenesis-associated 31 subfamily D, member 1D. | Testis-expressed 48. | 0.857 |
Spata31d1d | Tmco5 | ENSMUSP00000128200 | ENSMUSP00000028834 | Spermatogenesis-associated 31 subfamily D, member 1D. | Transmembrane and coiled-coil domain-containing protein 5A; Belongs to the TMCO5 family. | 0.715 |