STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpl1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA. (165 aa)    
Predicted Functional Partners:
Rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 
 0.999
Rps11
40S ribosomal protein S11.
  
 
 0.999
Rpl19
60S ribosomal protein L19.
   
 
 0.999
Rack1
Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to and stabilizes a [...]
   
 
 0.999
Rpl24
60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
   
 
 0.999
Rps26
40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.
   
 
 0.999
Rps3a1
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
   
 
 0.999
Rpl6
60S ribosomal protein L6; Component of the large ribosomal subunit.
   
 
 0.999
Rpl28
60S ribosomal protein L28; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL28 family.
   
 
 0.999
Rps3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...]
  
 
 0.999
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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