node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gin1 | Ppm1m | ENSMUSP00000108464 | ENSMUSP00000117908 | Gypsy retrotransposon integrase-like protein 1. | Protein phosphatase 1M; Belongs to the PP2C family. | 0.523 |
Gin1 | Rpp40 | ENSMUSP00000108464 | ENSMUSP00000130290 | Gypsy retrotransposon integrase-like protein 1. | Ribonuclease P protein subunit p40; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. | 0.544 |
Gin1 | Tmem116 | ENSMUSP00000108464 | ENSMUSP00000091917 | Gypsy retrotransposon integrase-like protein 1. | Transmembrane protein 116. | 0.523 |
Gin1 | Tmem60 | ENSMUSP00000108464 | ENSMUSP00000110914 | Gypsy retrotransposon integrase-like protein 1. | Transmembrane protein 60. | 0.530 |
Nt5dc2 | Ppm1m | ENSMUSP00000087680 | ENSMUSP00000117908 | 5'-nucleotidase domain-containing 2. | Protein phosphatase 1M; Belongs to the PP2C family. | 0.524 |
Ppef2 | Ppm1m | ENSMUSP00000144157 | ENSMUSP00000117908 | Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family. | Protein phosphatase 1M; Belongs to the PP2C family. | 0.503 |
Ppm1d | Ppm1m | ENSMUSP00000020835 | ENSMUSP00000117908 | Protein phosphatase 1D; Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (By similarity). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity. | Protein phosphatase 1M; Belongs to the PP2C family. | 0.577 |
Ppm1d | Pptc7 | ENSMUSP00000020835 | ENSMUSP00000051838 | Protein phosphatase 1D; Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (By similarity). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity. | Protein phosphatase PTC7 homolog; Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (By similarity). Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation (By similarity); Belongs to the PP2C family. | 0.417 |
Ppm1f | Ppm1m | ENSMUSP00000027373 | ENSMUSP00000117908 | Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis (By similarity). | Protein phosphatase 1M; Belongs to the PP2C family. | 0.647 |
Ppm1f | Pptc7 | ENSMUSP00000027373 | ENSMUSP00000051838 | Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis (By similarity). | Protein phosphatase PTC7 homolog; Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (By similarity). Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation (By similarity); Belongs to the PP2C family. | 0.555 |
Ppm1m | Gin1 | ENSMUSP00000117908 | ENSMUSP00000108464 | Protein phosphatase 1M; Belongs to the PP2C family. | Gypsy retrotransposon integrase-like protein 1. | 0.523 |
Ppm1m | Nt5dc2 | ENSMUSP00000117908 | ENSMUSP00000087680 | Protein phosphatase 1M; Belongs to the PP2C family. | 5'-nucleotidase domain-containing 2. | 0.524 |
Ppm1m | Ppef2 | ENSMUSP00000117908 | ENSMUSP00000144157 | Protein phosphatase 1M; Belongs to the PP2C family. | Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family. | 0.503 |
Ppm1m | Ppm1d | ENSMUSP00000117908 | ENSMUSP00000020835 | Protein phosphatase 1M; Belongs to the PP2C family. | Protein phosphatase 1D; Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (By similarity). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity. | 0.577 |
Ppm1m | Ppm1f | ENSMUSP00000117908 | ENSMUSP00000027373 | Protein phosphatase 1M; Belongs to the PP2C family. | Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis (By similarity). | 0.647 |
Ppm1m | Pptc7 | ENSMUSP00000117908 | ENSMUSP00000051838 | Protein phosphatase 1M; Belongs to the PP2C family. | Protein phosphatase PTC7 homolog; Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (By similarity). Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation (By similarity); Belongs to the PP2C family. | 0.611 |
Ppm1m | Ptpru | ENSMUSP00000117908 | ENSMUSP00000030741 | Protein phosphatase 1M; Belongs to the PP2C family. | Receptor-type tyrosine-protein phosphatase U; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis (By similarity); Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily. | 0.562 |
Ppm1m | Rpp40 | ENSMUSP00000117908 | ENSMUSP00000130290 | Protein phosphatase 1M; Belongs to the PP2C family. | Ribonuclease P protein subunit p40; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. | 0.483 |
Ppm1m | Tmem116 | ENSMUSP00000117908 | ENSMUSP00000091917 | Protein phosphatase 1M; Belongs to the PP2C family. | Transmembrane protein 116. | 0.523 |
Ppm1m | Tmem60 | ENSMUSP00000117908 | ENSMUSP00000110914 | Protein phosphatase 1M; Belongs to the PP2C family. | Transmembrane protein 60. | 0.523 |