node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc18 | Pradc1 | ENSMUSP00000036507 | ENSMUSP00000032080 | Coiled-coil domain-containing protein 18. | Protease-associated domain-containing protein 1. | 0.632 |
Ccdc18 | Prss37 | ENSMUSP00000036507 | ENSMUSP00000031967 | Coiled-coil domain-containing protein 18. | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | 0.488 |
Ccdc18 | Sfxn4 | ENSMUSP00000036507 | ENSMUSP00000118743 | Coiled-coil domain-containing protein 18. | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.454 |
Glrx5 | Sfxn4 | ENSMUSP00000021522 | ENSMUSP00000118743 | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase (By similarity). Required for normal iron homeostasis (By similarity). Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (By similarity). May protect cells against apoptosis due to reactive oxygen species and oxidative stress. | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.462 |
Nanos2 | Sfxn4 | ENSMUSP00000069765 | ENSMUSP00000118743 | Nanos homolog 2; Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for t [...] | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.449 |
Pradc1 | Ccdc18 | ENSMUSP00000032080 | ENSMUSP00000036507 | Protease-associated domain-containing protein 1. | Coiled-coil domain-containing protein 18. | 0.632 |
Pradc1 | Prss37 | ENSMUSP00000032080 | ENSMUSP00000031967 | Protease-associated domain-containing protein 1. | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | 0.629 |
Pradc1 | Sfxn4 | ENSMUSP00000032080 | ENSMUSP00000118743 | Protease-associated domain-containing protein 1. | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.537 |
Prr14l | Sfxn4 | ENSMUSP00000113259 | ENSMUSP00000118743 | Proline-rich 14-like. | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.504 |
Prss37 | Ccdc18 | ENSMUSP00000031967 | ENSMUSP00000036507 | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | Coiled-coil domain-containing protein 18. | 0.488 |
Prss37 | Pradc1 | ENSMUSP00000031967 | ENSMUSP00000032080 | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | Protease-associated domain-containing protein 1. | 0.629 |
Prss37 | Sfxn4 | ENSMUSP00000031967 | ENSMUSP00000118743 | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.456 |
Sfxn2 | Sfxn4 | ENSMUSP00000026011 | ENSMUSP00000118743 | Sideroflexin-2; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria. | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | 0.436 |
Sfxn4 | Ccdc18 | ENSMUSP00000118743 | ENSMUSP00000036507 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Coiled-coil domain-containing protein 18. | 0.454 |
Sfxn4 | Glrx5 | ENSMUSP00000118743 | ENSMUSP00000021522 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase (By similarity). Required for normal iron homeostasis (By similarity). Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (By similarity). May protect cells against apoptosis due to reactive oxygen species and oxidative stress. | 0.462 |
Sfxn4 | Nanos2 | ENSMUSP00000118743 | ENSMUSP00000069765 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Nanos homolog 2; Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for t [...] | 0.449 |
Sfxn4 | Pradc1 | ENSMUSP00000118743 | ENSMUSP00000032080 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Protease-associated domain-containing protein 1. | 0.537 |
Sfxn4 | Prr14l | ENSMUSP00000118743 | ENSMUSP00000113259 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Proline-rich 14-like. | 0.504 |
Sfxn4 | Prss37 | ENSMUSP00000118743 | ENSMUSP00000031967 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | 0.456 |
Sfxn4 | Sfxn2 | ENSMUSP00000118743 | ENSMUSP00000026011 | Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). | Sideroflexin-2; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria. | 0.436 |