STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr137cG protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. (423 aa)    
Predicted Functional Partners:
Tmem221
Transmembrane protein 221.
      
 0.741
Txndc16
Thioredoxin domain-containing protein 16.
   
  
 0.667
Tmem171
Transmembrane protein 171.
      
 0.653
Lrrc42
Leucine-rich repeat-containing protein 42; Belongs to the LRRC42 family.
      
 0.651
Tmem185a
Transmembrane protein 185A.
      
 0.617
Gpr157
G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger. Belongs to the G-protein coupled receptor 2 family.
      
 0.600
Haus8
HAUS augmin-like complex subunit 8; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to the HAUS8 family.
      
 0.592
Tmem211
Transmembrane protein 211.
   
  
 0.559
Hsf2bp
Heat shock factor 2-binding protein; Inhibits BNC1 transcriptional activity during spermatogenesis, probably by sequestering it in the cytoplasm. May be involved in modulating HSF2 activation in testis (By similarity).
      
 0.559
Olfr461
Olfactory receptor.
      
 0.555
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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