node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fam110a | Plekha2 | ENSMUSP00000105491 | ENSMUSP00000066546 | Protein FAM110A; Belongs to the FAM110 family. | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | 0.482 |
Fam110a | Tm2d2 | ENSMUSP00000105491 | ENSMUSP00000033961 | Protein FAM110A; Belongs to the FAM110 family. | TM2 domain-containing protein 2. | 0.690 |
Fam110a | Zmat4 | ENSMUSP00000105491 | ENSMUSP00000049430 | Protein FAM110A; Belongs to the FAM110 family. | Zinc finger matrin-type protein 4. | 0.599 |
Htra4 | Plekha2 | ENSMUSP00000081044 | ENSMUSP00000066546 | Serine protease HTRA4; Serine protease; Belongs to the peptidase S1C family. | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | 0.521 |
Htra4 | Tm2d2 | ENSMUSP00000081044 | ENSMUSP00000033961 | Serine protease HTRA4; Serine protease; Belongs to the peptidase S1C family. | TM2 domain-containing protein 2. | 0.432 |
Plekha1 | Plekha2 | ENSMUSP00000074675 | ENSMUSP00000066546 | Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | 0.658 |
Plekha1 | Plekha3 | ENSMUSP00000074675 | ENSMUSP00000107551 | Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). | Pleckstrin homology domain-containing family A member 3; Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4- phosphate (PtdIns4P) (By similarity). | 0.476 |
Plekha1 | Ptpn13 | ENSMUSP00000074675 | ENSMUSP00000048119 | Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). | Tyrosine-protein phosphatase non-receptor type 13; Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.907 |
Plekha2 | Fam110a | ENSMUSP00000066546 | ENSMUSP00000105491 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Protein FAM110A; Belongs to the FAM110 family. | 0.482 |
Plekha2 | Htra4 | ENSMUSP00000066546 | ENSMUSP00000081044 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Serine protease HTRA4; Serine protease; Belongs to the peptidase S1C family. | 0.521 |
Plekha2 | Plekha1 | ENSMUSP00000066546 | ENSMUSP00000074675 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). | 0.658 |
Plekha2 | Plekha3 | ENSMUSP00000066546 | ENSMUSP00000107551 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Pleckstrin homology domain-containing family A member 3; Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4- phosphate (PtdIns4P) (By similarity). | 0.518 |
Plekha2 | Plekha4 | ENSMUSP00000066546 | ENSMUSP00000051468 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.480 |
Plekha2 | Plekha8 | ENSMUSP00000066546 | ENSMUSP00000112466 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non- vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation [...] | 0.531 |
Plekha2 | Ptpn13 | ENSMUSP00000066546 | ENSMUSP00000048119 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Tyrosine-protein phosphatase non-receptor type 13; Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.921 |
Plekha2 | Tm2d2 | ENSMUSP00000066546 | ENSMUSP00000033961 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | TM2 domain-containing protein 2. | 0.594 |
Plekha2 | Utrn | ENSMUSP00000066546 | ENSMUSP00000076093 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Utrophin. | 0.589 |
Plekha2 | Zmat4 | ENSMUSP00000066546 | ENSMUSP00000049430 | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | Zinc finger matrin-type protein 4. | 0.494 |
Plekha3 | Plekha1 | ENSMUSP00000107551 | ENSMUSP00000074675 | Pleckstrin homology domain-containing family A member 3; Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4- phosphate (PtdIns4P) (By similarity). | Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). | 0.476 |
Plekha3 | Plekha2 | ENSMUSP00000107551 | ENSMUSP00000066546 | Pleckstrin homology domain-containing family A member 3; Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4- phosphate (PtdIns4P) (By similarity). | Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. | 0.518 |