node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2610507B11Rik | Nwd1 | ENSMUSP00000010421 | ENSMUSP00000124804 | Protein KIAA0100; May be involved in membrane trafficking. Belongs to the SABRE family. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.491 |
Abitram | Nwd1 | ENSMUSP00000047275 | ENSMUSP00000124804 | Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM family. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.483 |
Clvs2 | Nwd1 | ENSMUSP00000019920 | ENSMUSP00000124804 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.581 |
Clvs2 | Wdr74 | ENSMUSP00000019920 | ENSMUSP00000043315 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.607 |
Ints11 | Itprid2 | ENSMUSP00000030901 | ENSMUSP00000107415 | Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactam [...] | Protein ITPRID2. | 0.411 |
Ints11 | Nwd1 | ENSMUSP00000030901 | ENSMUSP00000124804 | Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactam [...] | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.564 |
Ints11 | Wdr82 | ENSMUSP00000030901 | ENSMUSP00000020490 | Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactam [...] | WD repeat-containing protein 82; Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Possible role in telomere length maintenance and in mRNA processin [...] | 0.763 |
Itprid2 | Ints11 | ENSMUSP00000107415 | ENSMUSP00000030901 | Protein ITPRID2. | Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactam [...] | 0.411 |
Itprid2 | Nwd1 | ENSMUSP00000107415 | ENSMUSP00000124804 | Protein ITPRID2. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.498 |
Magee2 | Nwd1 | ENSMUSP00000033575 | ENSMUSP00000124804 | Melanoma antigen, family E, 2. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.464 |
Nlrp2 | Nwd1 | ENSMUSP00000045077 | ENSMUSP00000124804 | NLR family, pyrin domain-containing 2. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.487 |
Nlrx1 | Nwd1 | ENSMUSP00000034621 | ENSMUSP00000124804 | NLR family member X1; Participates in antiviral signaling; Belongs to the NLRP family. | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | 0.563 |
Nwd1 | 2610507B11Rik | ENSMUSP00000124804 | ENSMUSP00000010421 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Protein KIAA0100; May be involved in membrane trafficking. Belongs to the SABRE family. | 0.491 |
Nwd1 | Abitram | ENSMUSP00000124804 | ENSMUSP00000047275 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM family. | 0.483 |
Nwd1 | Clvs2 | ENSMUSP00000124804 | ENSMUSP00000019920 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | 0.581 |
Nwd1 | Ints11 | ENSMUSP00000124804 | ENSMUSP00000030901 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactam [...] | 0.564 |
Nwd1 | Itprid2 | ENSMUSP00000124804 | ENSMUSP00000107415 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Protein ITPRID2. | 0.498 |
Nwd1 | Magee2 | ENSMUSP00000124804 | ENSMUSP00000033575 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | Melanoma antigen, family E, 2. | 0.464 |
Nwd1 | Nlrp2 | ENSMUSP00000124804 | ENSMUSP00000045077 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | NLR family, pyrin domain-containing 2. | 0.487 |
Nwd1 | Nlrx1 | ENSMUSP00000124804 | ENSMUSP00000034621 | NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels. | NLR family member X1; Participates in antiviral signaling; Belongs to the NLRP family. | 0.563 |