STRINGSTRING
Ces4a protein (mouse) - STRING interaction network
"Ces4a" - Carboxylesterase 4A in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
Ces4aCarboxylesterase 4A; Probable carboxylesterase (563 aa)    
Predicted Functional Partners:
Exoc3l
Exocyst complex component 3-like protein; As part of the exocyst, may play a role in regulated exocytosis of insulin granules; Belongs to the SEC6 family (739 aa)
     
   
  0.594
Tmed6
Transmembrane emp24 protein transport domain containing 6 (239 aa)
           
  0.551
Kctd19
BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerisation domain containing 19 (950 aa)
           
  0.522
Plekhg4
Pleckstrin homology domain containing, family G (with RhoGef domain) member 4 (1181 aa)
           
  0.495
Kri1
KRI1 homolog (S. cerevisiae); Belongs to the KRI1 family (705 aa)
           
  0.487
Dus2
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity). Negatively regulates the activation of EIF2AK2/PKR (By similarity); Belongs to the Dus family. Dus2 subfamily (493 aa)
           
  0.483
Ddx28
Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family (540 aa)
           
  0.448
Atp8b5
Phospholipid-transporting ATPase FetA; P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in phospholid transport across membranes and in acrosome formation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily (1183 aa)
     
   
  0.444
Acsm5
Acyl-coenzyme A synthetase ACSM5, mitochondrial; Has medium-chain fatty acid-CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity) (578 aa)
     
   
  0.439
Ranbp10
Ran-binding protein 10; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways (By similarity). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation (By similarity). Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function; Belongs to the RANBP9/10 family (648 aa)
           
  0.439
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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