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Ccdc85c protein (mouse) - STRING interaction network
"Ccdc85c" - Coiled-coil domain-containing protein 85C in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccdc85cCoiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia; Belongs to the CCDC85 family (420 aa)    
Predicted Functional Partners:
Arhgap23
Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (1488 aa)
     
 
  0.891
Arhgap21
Rho GTPase-activating protein 21; Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions (By similarity) (1945 aa)
     
 
  0.857
Sobp
Sine oculis-binding protein homolog; Implicated in development of the cochlea (864 aa)
     
   
  0.766
Ccdc184
Coiled-coil domain containing 184 (191 aa)
     
   
  0.713
Ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family (646 aa)
           
  0.662
Nrac
Nutritionally-regulated adipose and cardiac-enriched protein; RIKEN cDNA A530016L24 gene (165 aa)
           
  0.631
Snx16
Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling (By similarity); Belongs to the sorting nexin family (344 aa)
           
  0.618
Ufsp2
Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation (By similarity); Belongs to the peptidase C78 family (461 aa)
           
  0.597
Farsb
phenylalanyl-tRNA synthetase, beta subunit (589 aa)
           
  0.576
Arvcf
Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions (962 aa)
     
 
  0.563
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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