STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vmn2r116Vomeronasal type-2 receptor 116; Receptor for the Esp1 pheromone. Mediates the response to Esp1 which enhances female sexual receptive behavior (lordosis) upon male mounting, resulting in successful copulation. Belongs to the G-protein coupled receptor 3 family. (856 aa)    
Predicted Functional Partners:
Esp22
Exocrine gland-secreted peptide 22; Pheromone produced by juveniles which activates a small number of vomeronasal organ sensory neurons and exhibits a powerful inhibitory effect on adult male mating behavior.
      
 0.894
Vmn1r89
Vomeronasal type-1 receptor.
   
  
 0.722
Vmn1r69
Vomeronasal type-1 receptor.
   
  
 0.712
Esp36
Exocrine gland-secreting peptide 36.
      
 0.693
Vmn1r85
Vomeronasal type-1 receptor.
      
 0.692
Vmn1r49
Vomeronasal type-1 receptor 49; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.681
Vmn1r185
Vomeronasal type-1 receptor.
      
 0.676
Vmn1r216
Vomeronasal type-1 receptor.
  
  
 0.674
Esp1
Exocrine gland-secreted peptide 1; Male-specific phermone which is recognized by the Vmn2r116/V2rp5 receptor in the vomeronasal organ (VNO) and enhances female sexual receptive behavior (lordosis) upon male mounting, resulting in successful copulation. Belongs to the exocrine gland-secreted peptide family.
   
 
 0.665
Vmn1r215
Vomeronasal type-1 receptor.
  
  
 0.659
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (24%) [HD]