node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adam7 | Zfp511 | ENSMUSP00000022640 | ENSMUSP00000129154 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.623 |
Adamdec1 | Zfp511 | ENSMUSP00000022641 | ENSMUSP00000129154 | ADAM DEC1; May play an important role in the control of the immune response and during pregnancy. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.638 |
Erlin1 | Zfp511 | ENSMUSP00000071618 | ENSMUSP00000129154 | Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity). | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.657 |
Fam219a | Lrrc39 | ENSMUSP00000103687 | ENSMUSP00000029573 | Protein FAM219A; Belongs to the FAM219 family. | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | 0.600 |
Fam219a | Zfand2b | ENSMUSP00000103687 | ENSMUSP00000027394 | Protein FAM219A; Belongs to the FAM219 family. | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin- mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism th [...] | 0.694 |
Fam219a | Zfp511 | ENSMUSP00000103687 | ENSMUSP00000129154 | Protein FAM219A; Belongs to the FAM219 family. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.707 |
Lrrc39 | Fam219a | ENSMUSP00000029573 | ENSMUSP00000103687 | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | Protein FAM219A; Belongs to the FAM219 family. | 0.600 |
Lrrc39 | Zfand2b | ENSMUSP00000029573 | ENSMUSP00000027394 | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin- mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism th [...] | 0.439 |
Lrrc39 | Zfp511 | ENSMUSP00000029573 | ENSMUSP00000129154 | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.531 |
Srsf3 | Zfp511 | ENSMUSP00000117045 | ENSMUSP00000129154 | Serine/arginine-rich splicing factor 3; Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA- binding activity. [...] | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.551 |
Tsr3 | Zfp511 | ENSMUSP00000068511 | ENSMUSP00000129154 | Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.575 |
Tubgcp2 | Zfp511 | ENSMUSP00000026547 | ENSMUSP00000129154 | Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.556 |
Zfand2b | Fam219a | ENSMUSP00000027394 | ENSMUSP00000103687 | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin- mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism th [...] | Protein FAM219A; Belongs to the FAM219 family. | 0.694 |
Zfand2b | Lrrc39 | ENSMUSP00000027394 | ENSMUSP00000029573 | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin- mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism th [...] | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | 0.439 |
Zfand2b | Zfp511 | ENSMUSP00000027394 | ENSMUSP00000129154 | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin- mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism th [...] | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.574 |
Zfp511 | Adam7 | ENSMUSP00000129154 | ENSMUSP00000022640 | Zinc finger protein 511; May be involved in transcriptional regulation. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | 0.623 |
Zfp511 | Adamdec1 | ENSMUSP00000129154 | ENSMUSP00000022641 | Zinc finger protein 511; May be involved in transcriptional regulation. | ADAM DEC1; May play an important role in the control of the immune response and during pregnancy. | 0.638 |
Zfp511 | Erlin1 | ENSMUSP00000129154 | ENSMUSP00000071618 | Zinc finger protein 511; May be involved in transcriptional regulation. | Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity). | 0.657 |
Zfp511 | Fam219a | ENSMUSP00000129154 | ENSMUSP00000103687 | Zinc finger protein 511; May be involved in transcriptional regulation. | Protein FAM219A; Belongs to the FAM219 family. | 0.707 |
Zfp511 | Lrrc39 | ENSMUSP00000129154 | ENSMUSP00000029573 | Zinc finger protein 511; May be involved in transcriptional regulation. | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. | 0.531 |