node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Armc7 | Iffo2 | ENSMUSP00000046120 | ENSMUSP00000134062 | Armadillo repeat-containing protein 7. | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | 0.495 |
Cfdp1 | Desi2 | ENSMUSP00000034432 | ENSMUSP00000027783 | Craniofacial development protein 1; May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individual cell fate and survival. In embryonic cells, blockage of the function results in increased number of apoptotic cells, reduced proliferation, alterations in cell shape and fibronection matrix synthesis. | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | 0.505 |
Cfdp1 | Iffo2 | ENSMUSP00000034432 | ENSMUSP00000134062 | Craniofacial development protein 1; May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individual cell fate and survival. In embryonic cells, blockage of the function results in increased number of apoptotic cells, reduced proliferation, alterations in cell shape and fibronection matrix synthesis. | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | 0.424 |
Desi2 | Cfdp1 | ENSMUSP00000027783 | ENSMUSP00000034432 | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | Craniofacial development protein 1; May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individual cell fate and survival. In embryonic cells, blockage of the function results in increased number of apoptotic cells, reduced proliferation, alterations in cell shape and fibronection matrix synthesis. | 0.505 |
Desi2 | Heatr1 | ENSMUSP00000027783 | ENSMUSP00000054084 | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | HEAT repeat-containing 1. | 0.502 |
Desi2 | Hsdl1 | ENSMUSP00000027783 | ENSMUSP00000044371 | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. | 0.455 |
Desi2 | Iffo2 | ENSMUSP00000027783 | ENSMUSP00000134062 | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | 0.564 |
Heatr1 | Desi2 | ENSMUSP00000054084 | ENSMUSP00000027783 | HEAT repeat-containing 1. | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | 0.502 |
Heatr1 | Iffo2 | ENSMUSP00000054084 | ENSMUSP00000134062 | HEAT repeat-containing 1. | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | 0.455 |
Heatr1 | Wdr75 | ENSMUSP00000054084 | ENSMUSP00000027139 | HEAT repeat-containing 1. | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.999 |
Hsdl1 | Desi2 | ENSMUSP00000044371 | ENSMUSP00000027783 | Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | 0.455 |
Hsdl1 | Iffo2 | ENSMUSP00000044371 | ENSMUSP00000134062 | Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | 0.466 |
Iffo2 | Armc7 | ENSMUSP00000134062 | ENSMUSP00000046120 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | Armadillo repeat-containing protein 7. | 0.495 |
Iffo2 | Cfdp1 | ENSMUSP00000134062 | ENSMUSP00000034432 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | Craniofacial development protein 1; May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individual cell fate and survival. In embryonic cells, blockage of the function results in increased number of apoptotic cells, reduced proliferation, alterations in cell shape and fibronection matrix synthesis. | 0.424 |
Iffo2 | Desi2 | ENSMUSP00000134062 | ENSMUSP00000027783 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. | 0.564 |
Iffo2 | Heatr1 | ENSMUSP00000134062 | ENSMUSP00000054084 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | HEAT repeat-containing 1. | 0.455 |
Iffo2 | Hsdl1 | ENSMUSP00000134062 | ENSMUSP00000044371 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. | 0.466 |
Iffo2 | Wdr75 | ENSMUSP00000134062 | ENSMUSP00000027139 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.504 |
Iffo2 | Xrcc4 | ENSMUSP00000134062 | ENSMUSP00000022115 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. | DNA repair protein XRCC4; Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends (By similarity). | 0.619 |
Wdr75 | Heatr1 | ENSMUSP00000027139 | ENSMUSP00000054084 | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | HEAT repeat-containing 1. | 0.999 |