node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acap3 | Evi5l | ENSMUSP00000101209 | ENSMUSP00000135479 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. | Ecotropic viral integration site 5-like. | 0.406 |
Ankmy1 | Evi5l | ENSMUSP00000123787 | ENSMUSP00000135479 | Ankyrin repeat and MYND domain-containing protein 1. | Ecotropic viral integration site 5-like. | 0.517 |
Evi5l | Acap3 | ENSMUSP00000135479 | ENSMUSP00000101209 | Ecotropic viral integration site 5-like. | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. | 0.406 |
Evi5l | Ankmy1 | ENSMUSP00000135479 | ENSMUSP00000123787 | Ecotropic viral integration site 5-like. | Ankyrin repeat and MYND domain-containing protein 1. | 0.517 |
Evi5l | Mrpl30 | ENSMUSP00000135479 | ENSMUSP00000027256 | Ecotropic viral integration site 5-like. | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | 0.626 |
Evi5l | Pogk | ENSMUSP00000135479 | ENSMUSP00000127395 | Ecotropic viral integration site 5-like. | Pogo transposable element with KRAB domain. | 0.599 |
Evi5l | Rab23 | ENSMUSP00000135479 | ENSMUSP00000085625 | Ecotropic viral integration site 5-like. | Ras-related protein Rab-23; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with [...] | 0.478 |
Evi5l | Slc39a3 | ENSMUSP00000135479 | ENSMUSP00000128256 | Ecotropic viral integration site 5-like. | Zinc transporter ZIP3; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.465 |
Evi5l | Tbc1d30 | ENSMUSP00000135479 | ENSMUSP00000070488 | Ecotropic viral integration site 5-like. | TBC1 domain family member 30; GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By similarity). | 0.487 |
Evi5l | Tbc1d5 | ENSMUSP00000135479 | ENSMUSP00000024717 | Ecotropic viral integration site 5-like. | TBC1 domain family member 5; May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming ves [...] | 0.403 |
Mrpl30 | Evi5l | ENSMUSP00000027256 | ENSMUSP00000135479 | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | Ecotropic viral integration site 5-like. | 0.626 |
Mrpl30 | Pogk | ENSMUSP00000027256 | ENSMUSP00000127395 | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | Pogo transposable element with KRAB domain. | 0.680 |
Pogk | Evi5l | ENSMUSP00000127395 | ENSMUSP00000135479 | Pogo transposable element with KRAB domain. | Ecotropic viral integration site 5-like. | 0.599 |
Pogk | Mrpl30 | ENSMUSP00000127395 | ENSMUSP00000027256 | Pogo transposable element with KRAB domain. | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | 0.680 |
Rab23 | Evi5l | ENSMUSP00000085625 | ENSMUSP00000135479 | Ras-related protein Rab-23; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with [...] | Ecotropic viral integration site 5-like. | 0.478 |
Slc39a3 | Evi5l | ENSMUSP00000128256 | ENSMUSP00000135479 | Zinc transporter ZIP3; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | Ecotropic viral integration site 5-like. | 0.465 |
Tbc1d30 | Evi5l | ENSMUSP00000070488 | ENSMUSP00000135479 | TBC1 domain family member 30; GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By similarity). | Ecotropic viral integration site 5-like. | 0.487 |
Tbc1d30 | Tbc1d5 | ENSMUSP00000070488 | ENSMUSP00000024717 | TBC1 domain family member 30; GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By similarity). | TBC1 domain family member 5; May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming ves [...] | 0.440 |
Tbc1d5 | Evi5l | ENSMUSP00000024717 | ENSMUSP00000135479 | TBC1 domain family member 5; May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming ves [...] | Ecotropic viral integration site 5-like. | 0.403 |
Tbc1d5 | Tbc1d30 | ENSMUSP00000024717 | ENSMUSP00000070488 | TBC1 domain family member 5; May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming ves [...] | TBC1 domain family member 30; GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By similarity). | 0.440 |