STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H4f16H4 histone 16. (103 aa)    
Predicted Functional Partners:
Hist1h2ap
Histone cluster 1, H2ap.
 
 
 0.993
H2ac7
H2A clustered histone 7.
 
 
 0.993
H2ac13
H2A clustered histone 13.
 
 
 0.993
H2ac11
H2A clustered histone 11.
 
 
 0.993
Hist1h2ao
Histone cluster 1, H2ao.
 
 
 0.993
Hist1h2an
Histone cluster 1, H2an.
 
 
 0.993
H2ac8
H2A clustered histone 8.
 
 
 0.993
H2ac6
H2A clustered histone 6.
 
 
 0.993
H2ac4
Histone H2A type 1-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.992
H3c1
H3 clustered histone 1.
 
 
 
 0.987
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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