node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc38 | Ccdc39 | ENSMUSP00000089860 | ENSMUSP00000029222 | Coiled-coil domain-containing protein 38. | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | 0.446 |
Ccdc38 | Cfap73 | ENSMUSP00000089860 | ENSMUSP00000137554 | Coiled-coil domain-containing protein 38. | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | 0.618 |
Ccdc39 | Ccdc38 | ENSMUSP00000029222 | ENSMUSP00000089860 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Coiled-coil domain-containing protein 38. | 0.446 |
Ccdc39 | Cfap100 | ENSMUSP00000029222 | ENSMUSP00000126515 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | 0.401 |
Ccdc39 | Cfap73 | ENSMUSP00000029222 | ENSMUSP00000137554 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | 0.518 |
Ccdc39 | Tcte1 | ENSMUSP00000029222 | ENSMUSP00000109175 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC (By similarity). Required for sperm motility. | 0.462 |
Cfap100 | Ccdc39 | ENSMUSP00000126515 | ENSMUSP00000029222 | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | 0.401 |
Cfap100 | Cfap157 | ENSMUSP00000126515 | ENSMUSP00000099877 | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure ; Belongs to the CFAP157 family. | 0.484 |
Cfap100 | Cfap73 | ENSMUSP00000126515 | ENSMUSP00000137554 | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | 0.667 |
Cfap157 | Cfap100 | ENSMUSP00000099877 | ENSMUSP00000126515 | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure ; Belongs to the CFAP157 family. | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | 0.484 |
Cfap157 | Cfap73 | ENSMUSP00000099877 | ENSMUSP00000137554 | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure ; Belongs to the CFAP157 family. | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | 0.513 |
Cfap73 | Ccdc38 | ENSMUSP00000137554 | ENSMUSP00000089860 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Coiled-coil domain-containing protein 38. | 0.618 |
Cfap73 | Ccdc39 | ENSMUSP00000137554 | ENSMUSP00000029222 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | 0.518 |
Cfap73 | Cfap100 | ENSMUSP00000137554 | ENSMUSP00000126515 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family. | 0.667 |
Cfap73 | Cfap157 | ENSMUSP00000137554 | ENSMUSP00000099877 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure ; Belongs to the CFAP157 family. | 0.513 |
Cfap73 | Iqcd | ENSMUSP00000137554 | ENSMUSP00000091955 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Dynein regulatory complex protein 10; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC10 family. | 0.565 |
Cfap73 | Ppp1r42 | ENSMUSP00000137554 | ENSMUSP00000027049 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Protein phosphatase 1 regulatory subunit 42; Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis. | 0.521 |
Cfap73 | Prss37 | ENSMUSP00000137554 | ENSMUSP00000031967 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system (By similarity). | 0.558 |
Cfap73 | Rita1 | ENSMUSP00000137554 | ENSMUSP00000136946 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | RBPJ-interacting and tubulin-associated protein 1; Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity). | 0.643 |
Cfap73 | Tcte1 | ENSMUSP00000137554 | ENSMUSP00000109175 | Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family. | Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC (By similarity). Required for sperm motility. | 0.567 |