node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arl8a | Atp13a4 | ENSMUSP00000027684 | ENSMUSP00000138479 | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | Probable cation-transporting ATPase 13A4. | 0.595 |
Arl8a | Gga1 | ENSMUSP00000027684 | ENSMUSP00000035992 | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | ADP-ribosylation factor-binding protein GGA1; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface (By similarity). Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endo [...] | 0.516 |
Arl8a | Gga2 | ENSMUSP00000027684 | ENSMUSP00000033160 | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | ADP-ribosylation factor-binding protein GGA2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network. | 0.533 |
Arl8a | Neo1 | ENSMUSP00000027684 | ENSMUSP00000063656 | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | Neogenin; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. | 0.574 |
Arl8a | Slc25a36 | ENSMUSP00000027684 | ENSMUSP00000082302 | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | Solute carrier family 25 member 36; Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potentia [...] | 0.589 |
Atp13a4 | Arl8a | ENSMUSP00000138479 | ENSMUSP00000027684 | Probable cation-transporting ATPase 13A4. | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | 0.595 |
Atp13a4 | Ccdc144b | ENSMUSP00000138479 | ENSMUSP00000142910 | Probable cation-transporting ATPase 13A4. | Coiled-coil domain-containing 144B. | 0.445 |
Atp13a4 | Clmn | ENSMUSP00000138479 | ENSMUSP00000105563 | Probable cation-transporting ATPase 13A4. | Calmin. | 0.414 |
Atp13a4 | Cox20 | ENSMUSP00000138479 | ENSMUSP00000027781 | Probable cation-transporting ATPase 13A4. | Cytochrome c oxidase assembly protein COX20, mitochondrial; Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT- CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme. | 0.418 |
Atp13a4 | Gak | ENSMUSP00000138479 | ENSMUSP00000036705 | Probable cation-transporting ATPase 13A4. | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.533 |
Atp13a4 | Gga1 | ENSMUSP00000138479 | ENSMUSP00000035992 | Probable cation-transporting ATPase 13A4. | ADP-ribosylation factor-binding protein GGA1; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface (By similarity). Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endo [...] | 0.533 |
Atp13a4 | Gga2 | ENSMUSP00000138479 | ENSMUSP00000033160 | Probable cation-transporting ATPase 13A4. | ADP-ribosylation factor-binding protein GGA2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network. | 0.483 |
Atp13a4 | H6pd | ENSMUSP00000138479 | ENSMUSP00000030830 | Probable cation-transporting ATPase 13A4. | GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6-phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6-phosphogluconolactonase and cata [...] | 0.475 |
Atp13a4 | Neo1 | ENSMUSP00000138479 | ENSMUSP00000063656 | Probable cation-transporting ATPase 13A4. | Neogenin; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. | 0.592 |
Atp13a4 | Slc25a36 | ENSMUSP00000138479 | ENSMUSP00000082302 | Probable cation-transporting ATPase 13A4. | Solute carrier family 25 member 36; Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potentia [...] | 0.527 |
Ccdc144b | Atp13a4 | ENSMUSP00000142910 | ENSMUSP00000138479 | Coiled-coil domain-containing 144B. | Probable cation-transporting ATPase 13A4. | 0.445 |
Clmn | Atp13a4 | ENSMUSP00000105563 | ENSMUSP00000138479 | Calmin. | Probable cation-transporting ATPase 13A4. | 0.414 |
Cox20 | Atp13a4 | ENSMUSP00000027781 | ENSMUSP00000138479 | Cytochrome c oxidase assembly protein COX20, mitochondrial; Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT- CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme. | Probable cation-transporting ATPase 13A4. | 0.418 |
Gak | Atp13a4 | ENSMUSP00000036705 | ENSMUSP00000138479 | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Probable cation-transporting ATPase 13A4. | 0.533 |
Gga1 | Arl8a | ENSMUSP00000035992 | ENSMUSP00000027684 | ADP-ribosylation factor-binding protein GGA1; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface (By similarity). Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endo [...] | ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation (By similarity); Belongs to the small GTPase superfamily. Arf family. | 0.516 |