node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Coa5 | Coa6 | ENSMUSP00000027286 | ENSMUSP00000058279 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | 0.715 |
Coa5 | Cox10 | ENSMUSP00000027286 | ENSMUSP00000040138 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. | 0.631 |
Coa5 | Cox11 | ENSMUSP00000027286 | ENSMUSP00000020851 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. | 0.652 |
Coa5 | Cox15 | ENSMUSP00000027286 | ENSMUSP00000041820 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Cytochrome c oxidase assembly protein COX15 homolog; May be involved in the biosynthesis of heme A. | 0.598 |
Coa5 | Cox17 | ENSMUSP00000027286 | ENSMUSP00000113430 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Cytochrome c oxidase assembly protein 17, copper chaperone. | 0.783 |
Coa5 | Gm21987 | ENSMUSP00000027286 | ENSMUSP00000112386 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). | 0.781 |
Coa5 | Pet100 | ENSMUSP00000027286 | ENSMUSP00000137626 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Protein PET100 homolog, mitochondrial; Belongs to the PET100 family. | 0.676 |
Coa5 | Pet117 | ENSMUSP00000027286 | ENSMUSP00000139043 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Protein PET117 homolog, mitochondrial. | 0.781 |
Coa5 | Surf1 | ENSMUSP00000027286 | ENSMUSP00000015934 | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | Surfeit locus protein 1; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. | 0.611 |
Coa6 | Coa5 | ENSMUSP00000058279 | ENSMUSP00000027286 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | 0.715 |
Coa6 | Cox10 | ENSMUSP00000058279 | ENSMUSP00000040138 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. | 0.720 |
Coa6 | Cox11 | ENSMUSP00000058279 | ENSMUSP00000020851 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. | 0.827 |
Coa6 | Cox15 | ENSMUSP00000058279 | ENSMUSP00000041820 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase assembly protein COX15 homolog; May be involved in the biosynthesis of heme A. | 0.767 |
Coa6 | Cox16 | ENSMUSP00000058279 | ENSMUSP00000002757 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 ass [...] | 0.727 |
Coa6 | Cox17 | ENSMUSP00000058279 | ENSMUSP00000113430 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase assembly protein 17, copper chaperone. | 0.754 |
Coa6 | Gm21987 | ENSMUSP00000058279 | ENSMUSP00000112386 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). | 0.739 |
Coa6 | Pet100 | ENSMUSP00000058279 | ENSMUSP00000137626 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Protein PET100 homolog, mitochondrial; Belongs to the PET100 family. | 0.766 |
Coa6 | Pet117 | ENSMUSP00000058279 | ENSMUSP00000139043 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Protein PET117 homolog, mitochondrial. | 0.743 |
Coa6 | Surf1 | ENSMUSP00000058279 | ENSMUSP00000015934 | Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...] | Surfeit locus protein 1; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. | 0.697 |
Cox10 | Coa5 | ENSMUSP00000040138 | ENSMUSP00000027286 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. | Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. | 0.631 |