Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Blm | Exo1 | ENSRNOP00000015065 | ENSRNOP00000073202 | BLM RecQ-like helicase. | Exonuclease 1. | 0.991 |
Blm | Fen1 | ENSRNOP00000015065 | ENSRNOP00000027842 | BLM RecQ-like helicase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.847 |
Blm | Rad51 | ENSRNOP00000015065 | ENSRNOP00000053270 | BLM RecQ-like helicase. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.967 |
Blm | Rad52 | ENSRNOP00000015065 | ENSRNOP00000013070 | BLM RecQ-like helicase. | RAD52 homolog, DNA repair protein. | 0.928 |
Blm | Rbbp8 | ENSRNOP00000015065 | ENSRNOP00000017291 | BLM RecQ-like helicase. | DNA endonuclease RBBP8; Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. HR is restricted to S and G2 phases of the cell cycle and preferentially repairs DSBs resulting from replication fork collapse. Key determinant of DSB repair pathway choice, as it commits cells to HR by preventing classical non-homologous end-joining (NHEJ). Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phas [...] | 0.839 |
Blm | Rmi1 | ENSRNOP00000015065 | ENSRNOP00000025812 | BLM RecQ-like helicase. | RecQ mediated genome instability 1. | 0.996 |
Blm | Rpa1 | ENSRNOP00000015065 | ENSRNOP00000004229 | BLM RecQ-like helicase. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.996 |
Blm | Slc25a16 | ENSRNOP00000015065 | ENSRNOP00000000438 | BLM RecQ-like helicase. | DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair: recruited by BLM and mediates the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavag [...] | 0.970 |
Blm | Wdhd1 | ENSRNOP00000015065 | ENSRNOP00000015100 | BLM RecQ-like helicase. | WD repeat and HMG-box DNA binding protein 1 (Predicted). | 0.587 |
Blm | Wrn | ENSRNOP00000015065 | ENSRNOP00000055596 | BLM RecQ-like helicase. | WRN RecQ-like helicase. | 0.639 |
Exo1 | Blm | ENSRNOP00000073202 | ENSRNOP00000015065 | Exonuclease 1. | BLM RecQ-like helicase. | 0.991 |
Exo1 | Fen1 | ENSRNOP00000073202 | ENSRNOP00000027842 | Exonuclease 1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.882 |
Exo1 | Rad51 | ENSRNOP00000073202 | ENSRNOP00000053270 | Exonuclease 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.988 |
Exo1 | Rad52 | ENSRNOP00000073202 | ENSRNOP00000013070 | Exonuclease 1. | RAD52 homolog, DNA repair protein. | 0.940 |
Exo1 | Rbbp8 | ENSRNOP00000073202 | ENSRNOP00000017291 | Exonuclease 1. | DNA endonuclease RBBP8; Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. HR is restricted to S and G2 phases of the cell cycle and preferentially repairs DSBs resulting from replication fork collapse. Key determinant of DSB repair pathway choice, as it commits cells to HR by preventing classical non-homologous end-joining (NHEJ). Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phas [...] | 0.973 |
Exo1 | Rmi1 | ENSRNOP00000073202 | ENSRNOP00000025812 | Exonuclease 1. | RecQ mediated genome instability 1. | 0.905 |
Exo1 | Rpa1 | ENSRNOP00000073202 | ENSRNOP00000004229 | Exonuclease 1. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.856 |
Exo1 | Slc25a16 | ENSRNOP00000073202 | ENSRNOP00000000438 | Exonuclease 1. | DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair: recruited by BLM and mediates the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavag [...] | 0.990 |
Exo1 | Wdhd1 | ENSRNOP00000073202 | ENSRNOP00000015100 | Exonuclease 1. | WD repeat and HMG-box DNA binding protein 1 (Predicted). | 0.886 |
Exo1 | Wrn | ENSRNOP00000073202 | ENSRNOP00000055596 | Exonuclease 1. | WRN RecQ-like helicase. | 0.993 |
page 1 of 6