node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cep19 | Myef2 | ENSRNOP00000038182 | ENSRNOP00000072845 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Myelin expression factor 2. | 0.410 |
Cep19 | Zfp523 | ENSRNOP00000038182 | ENSRNOP00000074943 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.467 |
Ezh1 | Ezh2 | ENSRNOP00000027640 | ENSRNOP00000008149 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | Similar to Enhancer of zeste homolog 2 (ENX-1), isoform CRA_b. | 0.933 |
Ezh1 | Zfp523 | ENSRNOP00000027640 | ENSRNOP00000074943 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.539 |
Ezh2 | Ezh1 | ENSRNOP00000008149 | ENSRNOP00000027640 | Similar to Enhancer of zeste homolog 2 (ENX-1), isoform CRA_b. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.933 |
Ezh2 | Zfp523 | ENSRNOP00000008149 | ENSRNOP00000074943 | Similar to Enhancer of zeste homolog 2 (ENX-1), isoform CRA_b. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.486 |
Frs3 | Zfp523 | ENSRNOP00000019404 | ENSRNOP00000074943 | Fibroblast growth factor receptor substrate 3; Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2 (By similarity). | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.442 |
Mrps11 | Zfp523 | ENSRNOP00000025007 | ENSRNOP00000074943 | Similar to mitochondrial ribosomal protein S11 (Predicted), isoform CRA_a; Belongs to the universal ribosomal protein uS11 family. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.650 |
Myef2 | Cep19 | ENSRNOP00000072845 | ENSRNOP00000038182 | Myelin expression factor 2. | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | 0.410 |
Myef2 | Zfp523 | ENSRNOP00000072845 | ENSRNOP00000074943 | Myelin expression factor 2. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
Tcp11 | Zfp523 | ENSRNOP00000039755 | ENSRNOP00000074943 | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.561 |
Tmem14c | Zfp523 | ENSRNOP00000020737 | ENSRNOP00000074943 | Transmembrane protein 14C; Required for normal heme biosynthesis; Belongs to the TMEM14 family. | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.524 |
Ufm1 | Zfp523 | ENSRNOP00000054923 | ENSRNOP00000074943 | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1- ligase E3 enzyme UFL1. This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription. Other substrates may include DDRGK1 with which it may play [...] | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
Usp16 | Zfp523 | ENSRNOP00000002173 | ENSRNOP00000074943 | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiqu [...] | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
Zfp523 | Cep19 | ENSRNOP00000074943 | ENSRNOP00000038182 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | 0.467 |
Zfp523 | Ezh1 | ENSRNOP00000074943 | ENSRNOP00000027640 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.539 |
Zfp523 | Ezh2 | ENSRNOP00000074943 | ENSRNOP00000008149 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Similar to Enhancer of zeste homolog 2 (ENX-1), isoform CRA_b. | 0.486 |
Zfp523 | Frs3 | ENSRNOP00000074943 | ENSRNOP00000019404 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Fibroblast growth factor receptor substrate 3; Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2 (By similarity). | 0.442 |
Zfp523 | Mrps11 | ENSRNOP00000074943 | ENSRNOP00000025007 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Similar to mitochondrial ribosomal protein S11 (Predicted), isoform CRA_a; Belongs to the universal ribosomal protein uS11 family. | 0.650 |
Zfp523 | Myef2 | ENSRNOP00000074943 | ENSRNOP00000072845 | Zinc finger protein 76; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Myelin expression factor 2. | 0.482 |