node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdipt | Pim1 | ENSRNOP00000013691 | ENSRNOP00000000637 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] | 0.475 |
Dcp1a | Dcp1b | ENSRNOP00000021473 | ENSRNOP00000009832 | Decapping mRNA 1A. | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | 0.975 |
Dcp1a | Ddx6 | ENSRNOP00000021473 | ENSRNOP00000073900 | Decapping mRNA 1A. | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | 0.987 |
Dcp1a | Edc3 | ENSRNOP00000021473 | ENSRNOP00000026492 | Decapping mRNA 1A. | Enhancer of mRNA-decapping 3. | 0.993 |
Dcp1a | Pim1 | ENSRNOP00000021473 | ENSRNOP00000000637 | Decapping mRNA 1A. | Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] | 0.583 |
Dcp1a | Pim2 | ENSRNOP00000021473 | ENSRNOP00000011207 | Decapping mRNA 1A. | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. | 0.422 |
Dcp1b | Dcp1a | ENSRNOP00000009832 | ENSRNOP00000021473 | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | Decapping mRNA 1A. | 0.975 |
Dcp1b | Ddx6 | ENSRNOP00000009832 | ENSRNOP00000073900 | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | 0.978 |
Dcp1b | Edc3 | ENSRNOP00000009832 | ENSRNOP00000026492 | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | Enhancer of mRNA-decapping 3. | 0.989 |
Dcp1b | Pim1 | ENSRNOP00000009832 | ENSRNOP00000000637 | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] | 0.554 |
Ddx6 | Dcp1a | ENSRNOP00000073900 | ENSRNOP00000021473 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | Decapping mRNA 1A. | 0.987 |
Ddx6 | Dcp1b | ENSRNOP00000073900 | ENSRNOP00000009832 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | 0.978 |
Ddx6 | Edc3 | ENSRNOP00000073900 | ENSRNOP00000026492 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | Enhancer of mRNA-decapping 3. | 0.998 |
Ddx6 | Pim1 | ENSRNOP00000073900 | ENSRNOP00000000637 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] | 0.630 |
Ddx6 | Pim2 | ENSRNOP00000073900 | ENSRNOP00000011207 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. | 0.487 |
Edc3 | Dcp1a | ENSRNOP00000026492 | ENSRNOP00000021473 | Enhancer of mRNA-decapping 3. | Decapping mRNA 1A. | 0.993 |
Edc3 | Dcp1b | ENSRNOP00000026492 | ENSRNOP00000009832 | Enhancer of mRNA-decapping 3. | Similar to decapping enzyme Dcp1b (Predicted), isoform CRA_a. | 0.989 |
Edc3 | Ddx6 | ENSRNOP00000026492 | ENSRNOP00000073900 | Enhancer of mRNA-decapping 3. | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | 0.998 |
Edc3 | Pim1 | ENSRNOP00000026492 | ENSRNOP00000000637 | Enhancer of mRNA-decapping 3. | Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] | 0.580 |
Edc3 | Pim2 | ENSRNOP00000026492 | ENSRNOP00000011207 | Enhancer of mRNA-decapping 3. | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. | 0.428 |