STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bri3bpSimilar to BRI3-binding protein. (253 aa)    
Predicted Functional Partners:
Gnl3l
G protein nucleolar 3-like.
   
  
 0.697
Oprl1
Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociceptio [...]
  
   
 0.634
Commd2
COMM domain containing 2 (Predicted), isoform CRA_c.
      
 0.633
Tcp11l1
T-complex 11-like 1.
   
  
 0.615
Samd8
Sterile alpha motif domain-containing 8.
   
  
 0.573
Smim14
Small integral membrane protein 14.
      
 0.571
Agbl4
Peptidase_M14 domain-containing protein.
      
 0.570
Agbl4-2
ATP/GTP-binding protein-like 4.
      
 0.570
Dnajc18
DnaJ heat shock protein family (Hsp40) member C18.
   
  
 0.535
Ankrd28
Ankyrin repeat domain 28.
      
 0.508
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.